Publication Name	World Journal of Hematology
Manuscript ID	27283
Country	Colombia

Received	2016-05-22 13:44
Peer-Review Started	2016-05-23 15:08
To Make the First Decision	2016-07-27 08:18
Return for Revision	2016-07-30 18:24
Revised
Second Decision	2016-10-21 16:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-10-27 14:07
Articles in Press	2016-10-27 14:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-10-31 16:10
Publish the Manuscript Online	2016-11-03 15:47

ISSN	2218-6204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Hematology
Manuscript Type	Case Report
Article Title	Successful lower leg microsurgical reconstruction in homozygous sickle cell disease: Case report
Manuscript Source	Unsolicited Manuscript
All Author List	Carolina Posso and Francisco Cuéllar-Ambrosi
Funding Agency and Grant Number
Corresponding Author	Carolina Posso, MD, Plastic Surgeon-Microsurgeon, Plastic and Reconstructive Surgery Service, University of Antioquia, Antioquia, Medellín 050010238, Colombia. carolina.posso@gmail.com
Key Words	Sickle cell disease; Free flaps; Success rate; Microsurgical reconstruction; Ulcer
Core Tip	This is a case report of a successful microsurgical reconstruction in a patient with sickle cell disease who presented with an extensive lower leg ulcer during a 12-year course of the disease. We provide several recommendations for plasmapheresis and blood transfusions before the surgical reconstruction, and the anticoagulation protocol during the procedure and the postoperative period. This case description is intended to increase our colleagues’ motivation to perform microsurgical reconstruction with a safer approach in the presence of hematologic diseases with elevated risk of thrombosis.
Publish Date	2016-11-03 15:47
Citation	Posso C, Cuéllar-Ambrosi F. Successful lower leg microsurgical reconstruction in homozygous sickle cell disease: Case report. World J Hematol 2016; 5(4): 94-98
URL	http://www.wjgnet.com/2218-6204/full/v5/i4/94.htm
DOI	http://dx.doi.org/10.5315/wjh.v5.i4.94

Full Article (PDF)	WJH-5-94.pdf
Full Article (Word)	WJH-5-94.doc
Manuscript File	27283-Review.doc
Answering Reviewers	27283-Answering reviewers.pdf
Audio Core Tip	27283-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	27283-Conflict-of-interest statement.pdf
Copyright License Agreement	27283-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	27283-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	27283-Language certificate.pdf
Peer-review Report	27283-Peer-review(s).pdf
Scientific Misconduct Check	27283-Scientific misconduct check.pdf
Scientific Editor Work List	27283-Scientific editor work list.pdf