Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	27300
Country	Italy

Received	2016-05-23 08:53
Peer-Review Started	2016-05-23 09:53
To Make the First Decision	2016-07-04 15:33
Return for Revision	2016-07-06 17:21
Revised	2016-07-06 23:33
Second Decision	2016-08-11 10:52
Accepted by Journal Editor-in-Chief	2016-08-11 22:17
Accepted by Executive Editor-in-Chief	2016-08-18 11:27
Articles in Press	2016-08-18 11:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-10-24 14:28
Publish the Manuscript Online	2016-10-31 09:01

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Local ablative treatments for hepatocellular carcinoma: An updated review
Manuscript Source	Invited Manuscript
All Author List	Antonio Facciorusso, Gaetano Serviddio and Nicola Muscatiello
Funding Agency and Grant Number
Corresponding Author	Antonio Facciorusso, MD, Gastroenterology Unit, Department of Medical and Surgical Sciences, University of Foggia, Viale L. Pinto, 1, 71100 Foggia, Italy. antonio.facciorusso@virgilio.it
Key Words	Liver cancer; Hepatocellular carcinoma; Radiofrequency ablation; Microwave ablation; Radiofrequency ablation
Core Tip	Ablative treatments currently represent the first-line option for the treatment of early stage unresectable hepatocellular carcinoma. Among ablative therapies, radiofrequency ablation has gained a pivotal role due to its efficacy, with a reported 5-year survival rate of 40%-70%, and safety. Among other thermal treatments, microwave ablation, high-intensity focused ultrasound ablation, laser ablation, and cryoablation, are less investigated but showed promising results.
Publish Date	2016-10-31 09:01
Citation	Facciorusso A, Serviddio G, Muscatiello N. Local ablative treatments for hepatocellular carcinoma: An updated review. World J Gastrointest Pharmacol Ther 2016; 7(4): 477-489
URL	http://www.wjgnet.com/2150-5349/full/v7/i4/477.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v7.i4.477

Full Article (PDF)	WJGPT-7-477.pdf
Full Article (Word)	WJGPT-7-477.doc
Manuscript File	27300-Review.docx
Answering Reviewers	27300-Answering reviewers.pdf
Audio Core Tip	27300-Audio core tip.wma
Conflict-of-Interest Disclosure Form	27300-Conflict-of-interest statement.pdf
Copyright License Agreement	27300-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20160522223903.docx
Peer-review Report	27300-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	27300-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	27300-Scientific misconduct check.pdf
Scientific Editor Work List	27300-Scientific editor work list.pdf