Publication Name	World Journal of Nephrology
Manuscript ID	27566
Country	Canada

Received	2016-06-05 19:37
Peer-Review Started	2016-06-09 16:52
To Make the First Decision	2016-07-05 12:29
Return for Revision	2016-07-18 09:54
Revised	2016-07-29 04:54
Second Decision	2016-09-30 11:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-01-14 14:22
Articles in Press	2017-01-14 14:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-01 20:27
Publish the Manuscript Online	2017-03-05 19:09

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Urology & Nephrology
Manuscript Type	Retrospective Study
Article Title	Acute kidney injury following spinal instrumentation surgery in children
Manuscript Source	Invited Manuscript
All Author List	Jasper J Jöbsis, Abdullah Alabbas, Ruth Milner, Christopher Reilly, Kishore Mulpuri and Cherry Mammen
Funding Agency and Grant Number
Corresponding Author	Jasper J Jöbsis, MD, Department of Paediatrics, Tergooi Hospital, Rijksstraatweg 1, 1261 AN Blaricum, The Netherlands. jjobsis@tergooi.nl
Key Words	Acute kidney injury; Epidemiology; Acute Kidney Injury Network; Spinal surgery; Children
Core Tip	We are the first to report a high incidence of acute kidney injury (AKI) of 17% in children undergoing orthopaedic spinal instrumentation surgery utilizing the Acute Kidney Injury Network definition. A relationship was observed between the development of AKI and the use of nephrotoxins including non-steroidal anti-inflammatory drugs and lower amounts of intravenous fluid administered peri-operatively. These results suggest that there are modifiable AKI risk factors with the potential of reducing AKI incidence in this understudied population. Further prospective studies with the use of novel AKI biomarkers are needed to validate our novel results.
Publish Date	2017-03-05 19:09
Citation	Jöbsis JJ, Alabbas A, Milner R, Reilly C, Mulpuri K, Mammen C. Acute kidney injury following spinal instrumentation surgery in children. World J Nephrol 2017; 6(2): 79-85
URL	http://www.wjgnet.com/2220-6124/full/v6/i2/79.htm
DOI	http://dx.doi.org/10.5527/wjn.v6.i2.79

Full Article (PDF)	WJN-6-79.pdf
Full Article (Word)	WJN-6-79.doc
Manuscript File	27566-Review.docx
Answering Reviewers	27566-Answering reviewers.pdf
Audio Core Tip	27566-Audio core tip.mp3
Biostatistics Review Certificate	27566-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	27566-Conflict-of-interest statement.pdf
Copyright License Agreement	27566-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160605035620.docx
Institutional Review Board Approval Form or Document	27566-Institutional review board statement.pdf
Peer-review Report	27566-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	27566-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	27566-Scientific misconduct check.pdf
Scientific Editor Work List	27566-Scientific editor work list.pdf