Publication Name	World Journal of Hepatology
Manuscript ID	27692
Country	Türkiye

Received	2016-06-12 09:37
Peer-Review Started	2016-06-17 12:13
To Make the First Decision	2016-07-04 16:04
Return for Revision	2016-07-11 14:55
Revised	2016-07-26 21:28
Second Decision	2016-09-12 09:54
Accepted by Journal Editor-in-Chief	2016-09-15 19:29
Accepted by Company Editor-in-Chief	2016-09-22 14:45
Articles in Press	2016-09-22 14:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-11 16:04
Publish the Manuscript Online	2016-11-16 10:47

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Toll-like receptors in pathophysiology of liver diseases
Manuscript Source	Invited Manuscript
All Author List	Safak Kiziltas
Funding Agency and Grant Number
Corresponding Author	Safak Kiziltas, MD, Assistant Professor, Department of Gastroenterology, Baskent University Istanbul Hospital, Oymaci Street, No:7, 34662 Altunizade, Istanbul, Turkey. safakkiziltas@hotmail.com
Key Words	Toll-like receptors; Innate immunity; Liver disease; Pathophysiology; Signaling
Core Tip	Toll-like receptors (TLRs) are known to be pattern recognition receptors that recognize pathogen- and damage-associated molecular pattern molecules and thus participate in the activation of innate immune system. TLR signaling plays a significant role in liver diseases, whereas inflammatory or immune pathologies targeting distinct liver cells are based on complex immune responses. Herein, we review the current data on TLR signaling, hepatic expression of TLRs and associated ligands, as well as the contribution of TLRs to the pathophysiology of hepatic diseases.
Publish Date	2016-11-16 10:47
Citation	Kiziltas S. Toll-like receptors in pathophysiology of liver diseases. World J Hepatol 2016; 8(32): 1354-1369
URL	http://www.wjgnet.com/1948-5182/full/v8/i32/1354.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i32.1354

Full Article (PDF)	WJH-8-1354.pdf
Full Article (Word)	WJH-8-1354.doc
Manuscript File	27692-Review.doc
Answering Reviewers	27692-Answering reviewers.pdf
Audio Core Tip	27692-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	27692-Conflict-of-interest statement.pdf
Copyright License Agreement	27692-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	27692-Language certificate.pdf
Peer-review Report	27692-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	27692-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	27692-Scientific misconduct check.pdf
Scientific Editor Work List	27692-Scientific editor work list.pdf