BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/3/2017 11:25:00 AM | Browse: 912 | Download: 1826
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 27712
Country/Territory Germany
Received
2016-06-13 08:42
Peer-Review Started
2016-06-13 17:04
To Make the First Decision
2016-07-04 15:33
Return for Revision
2016-07-07 17:18
Revised
2016-08-30 19:38
Second Decision
2016-11-01 09:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-11-17 13:53
Articles in Press
2016-11-17 13:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-01-10 15:55
Publish the Manuscript Online
2017-02-03 11:25
ISSN 2219-2808 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Prospective Study
Article Title Off-label-use of sulfur-hexafluoride in voiding urosonography for diagnosis of vesicoureteral reflux in children: A survey on adverse events
Manuscript Source Invited Manuscript
All Author List Alexander Sauer, Clemens Wirth, Isabel Platzer, Henning Neubauer, Simon Veldhoen, Alexander Dierks, Reinhard Kaiser, Andreas Kunz, Meinrad Beer and Thorsten Bley
Funding Agency and Grant Number
Corresponding Author Dr. Alexander Sauer, Section of Pediatric Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Oberduerrbacher Straße 6, 97080 Wuerzburg, Germany. sauer_a4@ukw.de
Key Words Voiding urosonography; Ultrasound contrast agent; Vesicoureteral reflux; SonoVue; Adverse events; Sulfur hexafluoride
Core Tip This was a two-center study on 531 children with suspected or proven vesicoureteral reflux undergoing off-label voiding urosonography using sulfur hexafluoride (SH). We investigated the SH risk profile with intravesical administration. No acute allergic adverse event was observed with the off-label-use of SH for radiation free assessment of vesicoureteral reflux. Only a few subacute, minor-to-moderate adverse events were reported (4.1%). Hints of self-limited minor allergic reaction related to intravesical administration of sulfur hexafluoride were reported in less than 1%. This underlines the demand for an approval of SH in pediatric applications.
Publish Date 2017-02-03 11:25
Citation Sauer A, Wirth C, Platzer I, Neubauer H, Veldhoen S, Dierks A, Kaiser R, Kunz A, Beer M, Bley T. Off-label-use of sulfur-hexa¬fluoride in voiding urosonography for diagnosis of vesicoureteral reflux in children: A survey on adverse events. World J Clin Pediatr 2017; 6(1): 52-59
URL http://www.wjgnet.com/2219-2808/full/v6/i1/52.htm
DOI http://dx.doi.org/10.5409/wjcp.v6.i1.52
Full Article (PDF) WJCP-6-52.pdf
Full Article (Word) WJCP-6-52.doc
Manuscript File 27712-Review.docx
Answering Reviewers 27712-Answering reviewers.pdf
Audio Core Tip 27712-Audio core tip.mp3
Biostatistics Review Certificate 27712-Biostatistics statement.pdf
Clinical Trial Registration Statement 27712-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 27712-Conflict-of-interest statement.pdf
Copyright License Agreement 27712-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 27712-Clinical trial registration statement.pdf
Institutional Review Board Approval Form or Document 27712-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 27712-Language certificate.pdf
Peer-review Report 27712-Peer-review(s).pdf
Scientific Misconduct Check 27712-Scientific misconduct check.pdf
Scientific Editor Work List 27712-Scientific editor work list.pdf