| Category |
Oncology |
| Manuscript Type |
Autobiography |
| Article Title |
Annexin A2 silencing inhibits invasion, migration, and tumorigenic potential of hepatoma cells
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Hai-Jian Zhang, Deng-Fu Yao, Min Yao, Hua Huang, Li Wang, Mei-Juan Yan, Xiao-Di Yan, Xing Gu, Wei Wu and Shao-Lin Lu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Society Development of Nantong |
HS2012034 |
| Jiangsu Health Projects |
BL2012053 |
| Jiangsu Health Projects |
K201102 |
| Priority Academic Program Development of Jiangsu, and the International S and T Cooperation Program of China |
2013DFA32150 |
|
| Corresponding Author |
Deng-Fu Yao, MD, PhD, Professor, Research Centre of Clinical Medicine, Affiliated Hospital of Nantong University, 20 West Temple Road, Nantong 226001, Jiangsu Province, China. yaodf@ahnmc.com
|
| Key Words |
Tumorigenic potential; Migration; Invasion; Hepatocellular carcinoma; Small hairpin RNA; Annexin A2 |
| Core Tip |
The overexpression of annexin A2 (ANXA2) is closely related to the high metastasis potential and invasion ability of HCC cells, and ANXA2 deficiency inhibits the invasion, migration, and tumorigenic potential of hepatocellular carcinoma (HCC) cells, which not only provides further insight into the pathogenesis of HCC but also provides a potential predictive biomarker for HCC prognosis and a potential therapeutic target.
|
| Publish Date |
2013-06-28 23:55 |
| Citation |
Zhang HJ, Yao DF, Yao M, Huang H, Wang L, Yan MJ, Yan XD, Gu X, Wu W, Lu SL. Annexin A2 silencing inhibits invasion, migration, and tumorigenic potential of hepatoma cells. World J Gastroenterol 2013; 19(24): 3792-3801 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i24/3792.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i24.3792 |
