Publication Name	World Journal of Clinical Cases
Manuscript ID	27905
Country	Japan

Received	2016-06-22 14:19
Peer-Review Started	2016-06-27 10:27
To Make the First Decision	2016-08-05 15:23
Return for Revision	2016-08-11 15:24
Revised	2016-08-17 12:22
Second Decision	2016-10-14 14:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-10-27 17:32
Articles in Press	2016-10-27 17:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-01-03 08:20
Publish the Manuscript Online	2017-01-09 11:21

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Basic Study
Article Title	Inverse correlation between CD8+ inflammatory cells and E-cadherin expression in gallbladder cancer: Tissue microarray and imaging analysis
Manuscript Source	Invited Manuscript
All Author List	Keita Kai, Masanori Masuda and Shinichi Aishima
Funding Agency and Grant Number
Corresponding Author	Dr. Keita Kai, Department of Pathology, Saga University Hospital, Nabeshima 5-1-1, Saga 849-8501, Japan. kaikeit@cc.saga-u.ac.jp
Key Words	E-cadherin; Inflammation; CD8; Gallbladder cancer; Tissue microarray
Core Tip	We analyzed the association between the expression of E-cadherin in tumor cells and the type and amount of inflammatory cells infiltrating into the invasive portion of gallbladder cancer, using tissue microarray and imaging analyses. The results indicated an inverse correlation of CD8+ T cell infiltration and E-cadherin expression by cancer cells at invasive areas of gallbladder cancer. Further analyses are essential to test these results.
Publish Date	2017-01-09 11:21
Citation	Kai K, Masuda M, Aishima S. Inverse correlation between CD8+ inflammatory cells and E-cadherin expression in gallbladder cancer: Tissue microarray and imaging analysis. World J Clin Cases 2017; 5(1): 1-8
URL	http://www.wjgnet.com/2307-8960/full/v5/i1/1.htm
DOI	http://dx.doi.org/10.12998/wjcc.v5.i1.1

Full Article (PDF)	WJCC-5-1.pdf
Full Article (Word)	WJCC-5-1.doc
Manuscript File	27905-Review.docx
Answering Reviewers	27905-Answering reviewers.pdf
Audio Core Tip	27905-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	27905-Conflict-of-interest statement.pdf
Copyright License Agreement	27905-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160621111937.pdf
Institutional Review Board Approval Form or Document	27905-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	27905-Language certificate.pdf
Peer-review Report	27905-Peer-review(s).pdf
Scientific Misconduct Check	27905-Scientific misconduct check.pdf
Scientific Editor Work List	27905-Scientific editor work list.pdf