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Articles Published Processes
12/27/2016 8:31:00 AM | Browse: 1520 | Download: 1864
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Received |
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2016-06-22 14:48 |
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Peer-Review Started |
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2016-06-23 17:28 |
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To Make the First Decision |
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2016-08-10 14:56 |
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Return for Revision |
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2016-08-11 15:02 |
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Revised |
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2016-09-13 23:44 |
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Second Decision |
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2016-10-21 10:24 |
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Accepted by Journal Editor-in-Chief |
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2016-10-21 14:58 |
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Accepted by Executive Editor-in-Chief |
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2016-11-02 16:00 |
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Articles in Press |
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2016-11-02 16:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-12-19 08:34 |
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Publish the Manuscript Online |
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2016-12-27 08:31 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Fractionation of gamma-glutamyltransferase in patients with nonalcoholic fatty liver disease and alcoholic liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shigeo Sueyoshi, Setsu Sawai, Mamoru Satoh, Masanori Seimiya, Kazuyuki Sogawa, Atsushi Fukumura, Mikihiro Tsutsumi and Fumio Nomura |
| Funding Agency and Grant Number |
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| Corresponding Author |
Fumio Nomura, MD, Professor, Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670,
Japan. fnomura@faculty.chiba-u.jp |
| Key Words |
Gamma-glutamyltransferase; f-GGT/t-GGT ratios; Alcoholic liver disease; Non-alcoholic fatty liver disease; Gel filtration liquid chromatography |
| Core Tip |
The aim of this study was to assess whether fractionation of serum gamma-glutamyltransferase (GGT) into four fractions by high-performance gel filtration chromatography is useful for the differential diagnosis of alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). In patients with ALD, small-GGT (s-GGT)/total GGT (t-GGT) ratios were significantly higher and free-GGT (f-GGT)/t-GGT ratios were lower than in those in NAFLD. Consequently, there were marked differences in the s-GGT/f-GGT ratio between ALD and NAFLD. These preliminary results indicate that a large-scale study to clarify the diagnostic values of serum GGT fractionation in the differential diagnosis of ALD and NAFLD is warranted.
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| Publish Date |
2016-12-27 08:31 |
| Citation |
Sueyoshi S, Sawai S, Satoh M, Seimiya M, Sogawa K, Fukumura A, Tsutsumi M, Nomura F. Fractionation of gamma-glutamyltransferase in patients with nonalcoholic fatty liver disease and alcoholic liver disease. World J Hepatol 2016; 8(36): 1610-1616 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i36/1610.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i36.1610 |
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