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Articles Published Processes
11/26/2016 6:56:00 PM | Browse: 990 | Download: 1972
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Received |
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2016-06-24 11:02 |
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Peer-Review Started |
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2016-06-24 16:06 |
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To Make the First Decision |
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2016-07-29 15:15 |
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Return for Revision |
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2016-07-29 18:58 |
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Revised |
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2016-08-19 11:24 |
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Second Decision |
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2016-09-02 18:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-09-08 13:21 |
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Articles in Press |
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2016-09-08 13:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-10-09 02:59 |
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Typeset the Manuscript |
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2016-11-21 00:29 |
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Publish the Manuscript Online |
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2016-11-26 18:57 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
IFIT1 polymorphisms predict interferon-α treatment efficiency for hepatitis B virus infection
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Dong-Ying Xie, Shi-Ming Wang, Jing-Min Yang, Liang-Hui Wang, Hong-Yan Chen, Cong Huai, Jia Shang, Qing Mao, Chun-Liang Lei, Guang-Han Luo, Ji Qian and Da-Ru Lu |
| Funding Agency and Grant Number |
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| Corresponding Author |
Da-Ru Lu, PhD, Professor, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, School of Life Sciences, Fudan University. Life Science Building, Jiangwan Campus of Fudan University, No. 2005 Songhu Road, Shanghai 200438, China. darulu@hotmail.com |
| Key Words |
Virological response; Hepatitis B virus infection; IFIT1; Interferon-α therapy; Polymorphism |
| Core Tip |
Interferon-α (IFNα) is the first line treatment for chronic hepatitis B virus (HBV) infection (CHB). However, its efficiency differs and biomarkers for predicting responses of IFNα are needed. The current study performed an epidemiologic study to investigate the association between Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) polymorphisms and clinical responses of IFNα treatment in newly diagnosed chronic HBV infection patients among Chinese population. We identified that IFIT1 polymorphism rs303218 could be a predictor for the end point virological response of IFNα therapy. The finding may provide insight to the potential role of IFIT1 in the individualized treatment of CHB in the future. |
| Publish Date |
2016-11-26 18:57 |
| Citation |
Xie DY, Wang SM, Yang JM, Wang LH, Chen HY, Huai C, Shang J, Mao Q, Lei CL, Luo GH, Qian J, Lu DR. IFIT1 polymorphisms predict interferon-α treatment efficiency for hepatitis B virus infection. World J Gastroenterol 2016; 22(44): 9813-9821 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i44/9813.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i44.9813 |
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