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Articles Published Processes
11/26/2016 6:56:00 PM | Browse: 1220 | Download: 1783
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Received |
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2016-06-29 16:39 |
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Peer-Review Started |
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2016-06-30 10:10 |
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To Make the First Decision |
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2016-08-08 13:34 |
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Return for Revision |
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2016-08-12 11:05 |
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Revised |
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2016-08-26 16:49 |
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Second Decision |
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2016-09-21 15:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-09-28 17:40 |
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Articles in Press |
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2016-09-28 17:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-11-10 18:27 |
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Publish the Manuscript Online |
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2016-11-26 18:57 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Clinical features of HBsAg seroclearance in hepatitis B virus carriers in South Korea: A retrospective longitudinal study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Young Min Park and Seong Gyu Lee |
| Funding Agency and Grant Number |
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| Corresponding Author |
Young Min Park, MD, PhD, Hepatology Center, Department of Internal Medicine and Biomedical Research Center, Bundang Jesaeng General Hospital, 20, Seohyeon-ro 180 beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do 13589, South Korea. ymp1@outlook.com |
| Key Words |
Hepatocellular carcinoma; Hepatitis B virus; Hepatitis B Surface antigen; HBsAg; Seroconversion; Hepatitis B e antigen; HBeAg; Liver cirrhosis |
| Core Tip |
In South Korea, where most hepatitis B virus carriers are infected with genotype C, hepatitis B surface antigen (HBsAg) seroclearance rate is 4.7%, and the incidence of hepatocellular carcinoma (HCC) after HBsAg loss is 4.8%. In patients with HBsAg seroclearance, the percentages of asymptomatic liver cirrhosis (LC) and HCC are 31% and 7.8% at enrollment, respectively. A signal-to-cutoff ratio of the qualitative HBsAg level of less than 1000 and its sequential decrease are worth noting as predictive markers of HBsAg loss. HCC surveillance should be continued after HBsAg seroclearance, particularly in patients with LC. |
| Publish Date |
2016-11-26 18:57 |
| Citation |
Park YM, Lee SG. Clinical features of HBsAg seroclearance in hepatitis B virus carriers in South Korea: A retrospective longitudinal study. World J Gastroenterol 2016; 22(44): 9836-9843 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i44/9836.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i44.9836 |
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