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Articles Published Processes
11/18/2016 3:13:00 PM | Browse: 1152 | Download: 2523
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Received |
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2016-07-11 09:24 |
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Peer-Review Started |
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2016-07-13 15:52 |
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To Make the First Decision |
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2016-08-22 14:28 |
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Return for Revision |
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2016-08-24 18:35 |
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Revised |
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2016-09-18 22:17 |
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Second Decision |
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2016-09-30 10:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-10-10 17:16 |
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Articles in Press |
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2016-10-10 17:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-10-16 12:33 |
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Typeset the Manuscript |
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2016-11-12 13:44 |
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Publish the Manuscript Online |
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2016-11-18 15:13 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Allergy |
Manuscript Type |
Retrospective Study |
Article Title |
Ceruloplasmin, a reliable marker of fibrosis in chronic hepatitis B virus patients with normal or minimally raised alanine aminotransferase
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Manuscript Source |
Invited Manuscript |
All Author List |
Da-Wu Zeng, Jing Dong, Jia-Ji Jiang, Yue-Yong Zhu and Yu-Rui Liu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Youth Foundation of the Health and Family Planning Commission of Fujian Province |
2014-1-55 |
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Corresponding Author |
Yue-Yong Zhu, MD, Liver Center, The First Affiliated Hospital, Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian Province, China. ezhu066@sina.com
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Key Words |
Chronic hepatitis B; Liver biopsy; Fibrosis; Cirrhosis; Ceruloplasmin |
Core Tip |
To date, few non-invasive approaches have been developed to evaluate liver fibrosis and no studies have proposed measuring ceruloplasmin (CP) levels for predicting liver fibrosis in chronic hepatitis B (CHB) virus patients with normal or minimally raised alanine aminotransferase (ALT). This study showed CP was independently and negatively associated with liver fibrosis. Furthermore, a simple and accurate CG model was developed to predict significant liver fibrosis and cirrhosis in CHB patients with normal or mildly elevated ALT. This model may be a valuable tool to replace liver biopsy in this category of hepatitis B virus-infected patients.
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Publish Date |
2016-11-18 15:13 |
Citation |
Zeng DW, Dong J, Jiang JJ, Zhu YY, Liu YR. Ceruloplasmin, a reliable marker of fibrosis in chronic hepatitis B virus patients with normal or minimally raised alanine aminotransferase. World J Gastroenterol 2016; 22(43): 9586-9594 |
URL |
http://www.wjgnet.com/1007-9327/full/v22/i43/9586.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v22.i43.9586 |
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