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12/20/2016 10:03:00 AM | Browse: 868 | Download: 1034
Publication Name World Journal of Cardiology
Manuscript ID 28343
Country/Territory United States
Received
2016-06-30 11:02
Peer-Review Started
2016-07-01 17:25
To Make the First Decision
2016-08-04 16:21
Return for Revision
2016-08-05 11:00
Revised
2016-09-07 00:00
Second Decision
2016-09-20 15:52
Accepted by Journal Editor-in-Chief
2016-09-20 20:33
Accepted by Company Editor-in-Chief
2016-10-09 10:36
Articles in Press
2016-10-09 10:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-12-09 13:46
Publish the Manuscript Online
2016-12-20 10:04
ISSN 1949-8462 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Review
Article Title Hematological disorders and pulmonary hypertension
Manuscript Source Invited Manuscript
All Author List Rajamma Mathew, Jing Huang, Joseph M Wu, John T Fallon and Michael H Gewitz
Funding Agency and Grant Number
Corresponding Author Rajamma Mathew, MD, Section of Pediatric Cardiology, New York Medical College, Rm A11, Basic Science Building, 15 Dana Rd, Valhalla, NY 10595, United States. rajamma_mathew@nymc.edu
Key Words Anemia; Hemolysis; Iron homeostasis; Myelofibrosis; Pulmonary hypertension
Core Tip Oxidant injury, inflammation, impaired nitric oxide bioavailability and coagulopathy that occur in hematological diseases lead to endothelial dysfunction and thrombo-embolism with subsequent development of pulmonary hypertension (PH). In addition, treatment used for these disorders such as immunosuppressive drugs, splenectomy, bone marrow transplantation and radiation therapy are also known to cause endothelial damage and thrombo-embolism leading to PH. Furthermore, there is a causal relationship between vascular and hematopoietic systems. Patients with chronic myeloproliferative diseases are at a risk of developing PH; and the occurrence of myelofibrosis contributing to impaired hematopoiesis is not uncommon in PH.
Publish Date 2016-12-20 10:04
Citation Mathew R, Huang J, Wu JM, Fallon JT, Gewitz MH. Hematolo­gical disorders and pulmonary hypertension. World J Cardiol 2016; 8(12): 703-718
URL http://www.wjgnet.com/1949-8462/full/v8/i12/703.htm
DOI http://dx.doi.org/10.4330/wjc.v8.i12.703
Full Article (PDF) WJC-8-703.pdf
Full Article (Word) WJC-8-703.doc
Manuscript File 28343-Review.doc
Answering Reviewers 28343-Answering reviewers.pdf
Audio Core Tip 28343-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 28343-Conflict-of-interest statement.pdf
Copyright License Agreement 28343-Copyright assignment.pdf
Peer-review Report 28343-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 28343-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 28343-Scientific misconduct check.pdf
Scientific Editor Work List 28343-Scientific editor work list.pdf