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Articles Published Processes
2/20/2017 5:58:00 PM | Browse: 908 | Download: 2336
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Received |
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2016-07-01 09:52 |
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Peer-Review Started |
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2016-07-01 16:22 |
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To Make the First Decision |
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2016-08-29 08:44 |
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Return for Revision |
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2016-09-02 10:17 |
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Revised |
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2016-09-13 00:00 |
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Second Decision |
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2016-09-30 13:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-10-10 17:29 |
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Articles in Press |
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2016-10-10 17:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-02-08 15:49 |
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Typeset the Manuscript |
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2017-02-14 17:24 |
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Publish the Manuscript Online |
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2017-02-20 17:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Jianpi Qingchang decoction alleviates ulcerative colitis by inhibiting nuclear factor-κB activation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lie Zheng, Ya-Li Zhang, Yan-Cheng Dai, Xuan Chen, De-Liang Chen, Yue-Ting Dai and Zhi-Peng Tang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
81403355 |
| the National Natural Science Foundation of China |
81573892 |
| 3-Year Action Plan for Shanghai Municipal Chinese Medicine Development Project |
ZY3-RCPY-2-2001 |
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| Corresponding Author |
Zhi-Peng Tang, MD, PhD, Professor, Director, Institute of Digestive Diseases, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai 200032, China. zhipengtang@sohu.com
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| Key Words |
Jianpi Qingchang decoction; Dextran sodium sulfate; Ulcerative colitis; Nuclear factor-κB; Inflammation |
| Core Tip |
Nuclear factor-kappa B (NF-κB) is a major transcription factor inducing the expression of inflammatory mediators, which plays a crucial role in the transcription in diverse immune responses, and its signaling has been confirmed to be a major pathway for ulcerative colitis. It is demonstrated in the current study that Jianpi Qingchang decoction (JPQCD), which can decrease levels of proinflammatory cytokines, plays a role in inhibiting nuclear translocation of NF-κB and phosphorylation of inhibitor of kappa B, thus indicating that JPQCD can suppress the activation of NF-κB signaling pathway. |
| Publish Date |
2017-02-20 17:58 |
| Citation |
Zheng L, Zhang YL, Dai YC, Chen X, Chen DL, Dai YT, Tang ZP. Jianpi Qingchang decoction alleviates ulcerative colitis by inhibiting nuclear factor-κB activation. World J Gastroenterol 2017; 23(7): 1180-1188 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i7/1180.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i7.1180 |
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