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2/20/2017 5:58:00 PM | Browse: 802 | Download: 1944
Publication Name World Journal of Gastroenterology
Manuscript ID 28443
Country/Territory China
Received
2016-07-01 09:52
Peer-Review Started
2016-07-01 16:22
To Make the First Decision
2016-08-29 08:44
Return for Revision
2016-09-02 10:17
Revised
2016-09-13 00:00
Second Decision
2016-09-30 13:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-10-10 17:29
Articles in Press
2016-10-10 17:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-02-08 15:49
Typeset the Manuscript
2017-02-14 17:24
Publish the Manuscript Online
2017-02-20 17:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Jianpi Qingchang decoction alleviates ulcerative colitis by inhibiting nuclear factor-κB activation
Manuscript Source Unsolicited Manuscript
All Author List Lie Zheng, Ya-Li Zhang, Yan-Cheng Dai, Xuan Chen, De-Liang Chen, Yue-Ting Dai and Zhi-Peng Tang
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China 81403355
the National Natural Science Foundation of China 81573892
3-Year Action Plan for Shanghai Municipal Chinese Medicine Development Project ZY3-RCPY-2-2001
Corresponding Author Zhi-Peng Tang, MD, PhD, Professor, Director, Institute of Digestive Diseases, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai 200032, China. zhipengtang@sohu.com
Key Words Jianpi Qingchang decoction; Dextran sodium sulfate; Ulcerative colitis; Nuclear factor-κB; Inflammation
Core Tip Nuclear factor-kappa B (NF-κB) is a major transcription factor inducing the expression of inflammatory mediators, which plays a crucial role in the transcription in diverse immune responses, and its signaling has been confirmed to be a major pathway for ulcerative colitis. It is demonstrated in the current study that Jianpi Qingchang decoction (JPQCD), which can decrease levels of proinflammatory cytokines, plays a role in inhibiting nuclear translocation of NF-κB and phosphorylation of inhibitor of kappa B, thus indicating that JPQCD can suppress the activation of NF-κB signaling pathway.
Publish Date 2017-02-20 17:58
Citation Zheng L, Zhang YL, Dai YC, Chen X, Chen DL, Dai YT, Tang ZP. Jianpi Qingchang decoction alleviates ulcerative colitis by inhibiting nuclear factor-κB activation. World J Gastroenterol 2017; 23(7): 1180-1188
URL http://www.wjgnet.com/1007-9327/full/v23/i7/1180.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i7.1180
Full Article (PDF) WJG-23-1180.pdf
Full Article (Word) WJG-23-1180.doc
Manuscript File 28443-Review.doc
Answering Reviewers 28443-Answering reviewers.pdf
Audio Core Tip 28443-Audio core tip.mp3
Biostatistics Review Certificate 28443-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28443-Conflict-of-interest statement.pdf
Copyright License Agreement 28443-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 28443-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 28443-Institutional animal care and use committee statementt.pdf
Institutional Review Board Approval Form or Document 28443-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 28443-Language certificate.pdf
Peer-review Report 28443-Peer-review(s).pdf
Scientific Misconduct Check 28433-Scientific misconduct check.pdf
Scientific Editor Work List 28443-Scientific editor work list.pdf