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Articles Published Processes
1/14/2017 10:42:00 AM | Browse: 1132 | Download: 2152
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Received |
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2016-07-01 09:04 |
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Peer-Review Started |
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2016-07-01 15:49 |
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To Make the First Decision |
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2016-08-08 13:32 |
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Return for Revision |
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2016-08-10 08:55 |
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Revised |
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2016-10-05 05:30 |
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Second Decision |
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2016-10-10 13:39 |
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Accepted by Journal Editor-in-Chief |
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2016-10-11 17:29 |
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Accepted by Executive Editor-in-Chief |
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2016-10-19 17:15 |
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Articles in Press |
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2016-10-19 17:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-01-04 22:28 |
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Publish the Manuscript Online |
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2017-01-14 10:27 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Physiology |
| Manuscript Type |
Basic Study |
| Article Title |
Sex differences and effects of oestrogen in rat gastric mucosal defence
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Richard Shore, Håkan Björne, Yoko Omoto, Anna Siemiatkowska, Jan-Åke Gustafsson, Mats Lindblad and Lena Holm |
| Funding Agency and Grant Number |
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| Corresponding Author |
Richard Shore, MD, Function Perioperative Medicine and Intensive Care, Karolinska University Hospital, Karolinska vägen, S-17176 Stockholm, Sweden. richard.shore@karolinska.se |
| Key Words |
Sex differences; Gastric mucosal defence; Blood flow; Oestrogen; Gastric physiology; Mucus |
| Core Tip |
We report a sex difference in absolute gastric mucosal blood flow using an in vivo rat experimental model. Male rats had approximately twice as high blood flow in the gastric corpus mucosa compared to females. Moreover, relative gastric mucosal blood flow decreased during oestrogen administration in males but not in females and the permeability of the gastric mucosa increased to a higher level in females than in males after taurocholate challenge. However, mean clearance increase, mucus thickness and accumulation rate and the expression of ERα, ERβ or calcitonin gene related peptide in the gastric mucosa did not differ significantly between the sexes. |
| Publish Date |
2017-01-14 10:27 |
| Citation |
Shore R, Björne H, Omoto Y, Siemiatkowska A, Gustafsson JÅ, Lindblad M, Holm L. Sex differences and effects of oestrogen in rat gastric mucosal defence. World J Gastroenterol 2017; 23(3): 426-436 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i3/426.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i3.426 |
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