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Articles Published Processes
9/30/2016 5:59:00 PM | Browse: 933 | Download: 1403
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Received |
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2016-07-05 11:24 |
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Peer-Review Started |
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2016-07-06 17:39 |
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To Make the First Decision |
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2016-07-29 16:26 |
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Return for Revision |
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2016-08-02 12:12 |
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Revised |
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2016-08-13 10:09 |
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Second Decision |
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2016-08-17 13:43 |
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Accepted by Journal Editor-in-Chief |
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2016-08-20 12:20 |
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Accepted by Executive Editor-in-Chief |
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2016-08-23 17:07 |
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Articles in Press |
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2016-08-23 17:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-09-20 17:56 |
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Publish the Manuscript Online |
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2016-09-30 18:06 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Editorial |
Article Title |
Impact of homeobox genes in gastrointestinal cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Moon Kyung Joo, Jong-Jae Park and Hoon Jai Chun |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Korean College of Helicobacter and Upper Gastrointestinal Research Foundation Grant |
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Korea University Grant |
K1512661 |
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Corresponding Author |
Hoon Jai Chun, MD, PhD, AGAF, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of Medicine, 126-1, Anam-dong 5 ga, Seongbuk-gu, Seoul 02841, South Korea. drchunhj@chol.com |
Key Words |
Homeobox genes; HOX genes; Caudal-related homeobox transcription factor 2; Gastrointestinal cancers; HOXB7 |
Core Tip |
Aberrant up- or downregulation of homeobox genes may play pivotal roles in the development and progression of gastrointestinal (GI) cancers. Core research in GI cancers has focused on non-HOX genes including caudal-related homeobox transcription factor 2. However, recent studies have demonstrated significant functions of specific HOX genes, including HOXB7, HOXA13, and HOXD10, in GI cancers. Here, we review the major research data concerning the deregulation of homeobox genes in GI cancers and their underlying mechanisms.
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Publish Date |
2016-09-30 18:06 |
Citation |
Joo MK, Park JJ, Chun HJ. Impact of homeobox genes in gastrointestinal cancer. World J Gastroenterol 2016; 22(37): 8247-8256 |
URL |
http://www.wjgnet.com/1007-9327/full/v22/i37/8247.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v22.i37.8247 |
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