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Articles Published Processes
12/6/2016 5:24:00 PM | Browse: 1314 | Download: 1941
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Received |
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2016-07-08 09:20 |
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Peer-Review Started |
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2016-07-11 16:35 |
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To Make the First Decision |
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2016-09-05 14:16 |
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Return for Revision |
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2016-09-07 09:58 |
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Revised |
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2016-09-20 15:56 |
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Second Decision |
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2016-11-07 09:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-11-13 15:32 |
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Articles in Press |
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2016-11-13 15:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-11-25 16:45 |
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Publish the Manuscript Online |
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2016-12-06 17:24 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Influence of capsaicin infusion on secondary peristalsis in patients with gastroesophageal reflux disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Tso-Tsai Liu, Chien-Lin Chen and Fabio Pace |
| Funding Agency and Grant Number |
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| Corresponding Author |
Chien-Lin Chen MD, PhD, Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, 707, Section 3, Chung-Yang Road, Hualien 97002,
Taiwan. harry.clchen@msa.hinet.net
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| Key Words |
Capsaicin; Esophageal motility; Secondary peristalsis; Esophageal manometry; Gastroesophageal reflux disease |
| Core Tip |
This clinical significance of this study is that acute esophageal infusion of capsaicin-containing red pepper sauce significantly enhances mechanosensitivity to distension-induced secondary peristalsis in patients with gastroesophageal reflux disease (GERD), which might be beneficial in reflux patient with hypomotility. Conversely, repeated esophageal exposure to capsaicin-containing red pepper sauce may reduce the efficiency of esophageal secondary peristalsis. Repeated capsaicin infusion may therefore reduce the protection of the esophagus by hampering the clearing of residue substance or refluxate in the esophagus, which may in turn prolong acid clearance in patients with GERD. |
| Publish Date |
2016-12-06 17:24 |
| Citation |
Yi CH, Lei WY, Hung JS, Liu TT, Chen CL, Pace F. Influence of capsaicin infusion on secondary peristalsis in patients with gastroesophageal reflux disease. World J Gastroenterol 2016; 22(45): 10045-10052 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i45/10045.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i45.10045 |
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