| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Meta-analysis of lymph node metastasis in Siewert type Ⅰ and Ⅱ T1 adenocarcinomas
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hiroki Osumi, Junko Fujisaki, Masami Omae, Tomoki Shimizu, Toshiyuki Yoshio, Akiyoshi Ishiyama, Toshiaki Hirasawa, Tomohiro Tsuchida, Yorimasa Yamamoto, Hiroshi Kawachi, Noriko Yamamoto and Masahiro Igarashi |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Junko Fujisaki, MD, PhD, Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan. junko.fujisaki@jfcr.or.jp |
| Key Words |
Siewert type Ⅰ and type Ⅱ adenocarcinomas; Lymph node metastasis |
| Core Tip |
We evaluated meta-analysis of the incidence of lymph node metastasis (LNM) in patients with Siewert type Ⅰ and type Ⅱ pT1 adenocarcinomas. Of previous 5 reports and our study, 12 of the 355 patients (3.38%, 95%CI: 1.5-5.2) in pT1a adenocarcinoma had LNM, whereas 91 of the 438 patients (20.7%, 95%CI: 16.9-24.5) in pT1b adenocarcinoma had LNM. We consider endoscopic submucosal dissection (ESD) to be a reasonable for patients that have well differentiated, limited to the mucosa, and within 30 mm in diameter with no lymphovascular invasion. For patients with T1b adenocarcinoma, especially invasion depth within 500 um from muscularis mucosae with no other risk factor for LNM, diagnostic ESD could be a treatment option. |
| Publish Date |
2016-12-20 16:10 |
| Citation |
Osumi H, Fujisaki J, Omae M, Shimizu T, Yoshio T, Ishiyama A, Hirasawa T, Tsuchida T, Yamamoto Y, Kawachi H, Yamamoto N, Igarashi M. Meta-analysis of lymph node metastasis in Siewert type Ⅰ and Ⅱ T1 adenocarcinomas. World J Meta-Anal 2016; 4(6): 118-123 |
| URL |
http://www.wjgnet.com/2308-3840/full/v4/i6/118.htm |
| DOI |
http://dx.doi.org/10.13105/wjma.v4.i6.118 |
