Publication Name	World Journal of Hepatology
Manuscript ID	28720
Country	Australia

Received	2016-07-13 10:54
Peer-Review Started	2016-07-14 17:03
To Make the First Decision	2016-09-07 14:53
Return for Revision	2016-09-09 13:58
Revised	2016-10-06 11:40
Second Decision	2016-10-13 12:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-10-24 15:27
Articles in Press	2016-10-24 15:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-06 18:01
Publish the Manuscript Online	2016-12-15 16:07

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Immune function biomarker QuantiFERON-monitor is associated with infection risk in cirrhotic patients
Manuscript Source	Invited Manuscript
All Author List	Siddharth Sood, Lijia Yu, Kumar Visvanathan, Peter William Angus, Paul John Gow and Adam Gareth Testro
Funding Agency and Grant Number
Corresponding Author	Dr. Siddharth Sood, MBBS, BMedSci, PhD, Head of Hepatology, Department of Gastroenterology and Hepatology, University of Melbourne, Royal Melbourne Hospital, Royal Parade, Parkville, VIC 3050, Australia. siddharth.sood@mh.org.au
Key Words	Infection; Biomarker; Immune dysfunction; Immune function; Immunosuppression; Liver; Immune system; Cirrhosis; Mortality
Core Tip	QuantiFERON-Monitor (QFM) is a net immune function biomarker that measures interferon-γ after stimulation of the innate and adaptive immune systems and is based on a readily available pathology platform. Measuring QFM in cirrhotic patients provides an objective marker of their immune dysfunction, which has otherwise been difficult to quantify. Low QFM is significantly associated with the risk of pre-transplant infection, and very low QFM may be associated with increased risk of mortality.
Publish Date	2016-12-15 16:07
Citation	Sood S, Yu L, Visvanathan K, Angus PW, Gow PJ, Testro AG. Immune function biomarker QuantiFERON-monitor is associated with infection risk in cirrhotic patients. World J Hepatol 2016; 8(35): 1569-1575
URL	http://www.wjgnet.com/1948-5182/full/v8/i35/1569.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i35.1569

Full Article (PDF)	WJH-8-1569.pdf
Full Article (Word)	WJH-8-1569.doc
Manuscript File	28720-Review.docx
Answering Reviewers	28720-Answering reviewers.pdf
Audio Core Tip	28720-Audio core tip.mp3
Clinical Trial Registration Statement	28720-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	28720-Conflict-of-interest statement.pdf
Copyright License Agreement	28720-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	28720-Clinical trial registration statement.pdf
Institutional Review Board Approval Form or Document	28720-Institutional review board statement.pdf
Peer-review Report	28720-Peer-review(s).pdf
Scientific Misconduct Check	28720-Scientific misconduct check.pdf
Scientific Editor Work List	28720-Scientific editor work list.pdf