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12/15/2016 4:06:00 PM | Browse: 1736 | Download: 3026
Publication Name World Journal of Hepatology
Manuscript ID 28720
Country Australia
Received
2016-07-13 10:54
Peer-Review Started
2016-07-14 17:03
First Decision by Editorial Office Director
Return for Revision
2016-09-09 13:58
Revised
2016-10-06 11:40
Publication Fee Transferred
Second Decision by Editor
2016-10-13 12:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2016-10-24 15:27
Articles in Press
2016-10-24 15:27
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-12-06 18:01
Publish the Manuscript Online
2016-12-15 16:07
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Immune function biomarker QuantiFERON-monitor is associated with infection risk in cirrhotic patients
Manuscript Source Invited Manuscript
All Author List Siddharth Sood, Lijia Yu, Kumar Visvanathan, Peter William Angus, Paul John Gow and Adam Gareth Testro
Funding Agency and Grant Number
Corresponding Author Dr. Siddharth Sood, MBBS, BMedSci, PhD, Head of Hepatology, Department of Gastroenterology and Hepatology, University of Melbourne, Royal Melbourne Hospital, Royal Parade, Parkville, VIC 3050, Australia. siddharth.sood@mh.org.au
Key Words Infection; Biomarker; Immune dysfunction; Immune function; Immunosuppression; Liver; Immune system; Cirrhosis; Mortality
Core Tip QuantiFERON-Monitor (QFM) is a net immune function biomarker that measures interferon-γ after stimulation of the innate and adaptive immune systems and is based on a readily available pathology platform. Measuring QFM in cirrhotic patients provides an objective marker of their immune dysfunction, which has otherwise been difficult to quantify. Low QFM is significantly associated with the risk of pre-transplant infection, and very low QFM may be associated with increased risk of mortality.
Publish Date 2016-12-15 16:07
Citation Sood S, Yu L, Visvanathan K, Angus PW, Gow PJ, Testro AG. Immune function biomarker QuantiFERON-monitor is associated with infection risk in cirrhotic patients. World J Hepatol 2016; 8(35): 1569-1575
URL http://www.wjgnet.com/1948-5182/full/v8/i35/1569.htm
DOI http://dx.doi.org/10.4254/wjh.v8.i35.1569
Full Article (PDF) WJH-8-1569.pdf
Full Article (Word) WJH-8-1569.doc