Publication Name	World Journal of Gastroenterology
Manuscript ID	28741
Country	United States

Received	2016-07-13 08:50
Peer-Review Started	2016-07-16 20:28
To Make the First Decision	2016-08-08 13:32
Return for Revision	2016-08-10 08:54
Revised	2016-09-03 02:06
Second Decision	2016-09-21 15:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-09-28 18:02
Articles in Press	2016-09-28 18:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-02-08 10:42
Publish the Manuscript Online	2017-02-26 18:20

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	TGR5 expression in benign, preneoplastic and neoplastic lesions of Barrett’s esophagus: Case series and findings
Manuscript Source	Unsolicited Manuscript
All Author List	Shivali Marketkar, Dan Li, Dongfang Yang and Weibiao Cao
Funding Agency and Grant Number
Corresponding Author	Weibiao Cao, MD, Department of Pathology, Rhode Island Hospital and Warren Alpert Medical School of Brown University, 593 Eddy St, APC12, Providence, RI 02903, United States. wcao@hotmail.com
Key Words	TGR5; Esophageal adenocarcinoma; Bile acid
Core Tip	The expression of a bile acid receptor TGR5 at moderate to strong intensity was significantly higher in high-grade dysplasia and esophageal adenocarcinoma (EA) cases than in BE or in low-grade dysplasia, suggesting that TGR5 may play an important role in the progression from Barrett’s esophagus to high-grade dysplasia and EA. TGR5 might be a potential marker for this progression. TGR5 staining intensity was not associated with the clinical stage, the pathological stage and the status of lymph node metastasis, indicating that TGR5 may not be a marker for the prognosis of EA.
Publish Date	2017-02-26 18:20
Citation	Marketkar S, Li D, Yang D, Cao W. TGR5 expression in benign, preneoplastic and neoplastic lesions of Barrett’s esophagus: Case series and findings. World J Gastroenterol 2017; 23(8): 1338-1344
URL	http://www.wjgnet.com/1007-9327/full/v23/i8/1338.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i8.1338

Full Article (PDF)	WJG-23-1338.pdf
Full Article (Word)	WJG-23-1338.doc
Manuscript File	28741-Review.doc
Answering Reviewers	28741-Answering reviewers.pdf
Audio Core Tip	28741-Audio core tip.mp3
Biostatistics Review Certificate	28741-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	28741-Conflict-of-interest statement.pdf
Copyright License Agreement	28741-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	28741-Institutional review board statement.pdf
Peer-review Report	28741-Peer-review(s).pdf
Scientific Misconduct Check	28741-Scientific misconduct check.pdf
Scientific Editor Work List	28741-Scientific editor work list.pdf