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Publication Name World Journal of Gastroenterology
Manuscript ID 28741
Country/Territory United States
Received
2016-07-13 08:50
Peer-Review Started
2016-07-16 20:28
To Make the First Decision
2016-08-08 13:32
Return for Revision
2016-08-10 08:54
Revised
2016-09-03 02:06
Second Decision
2016-09-21 15:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-09-28 18:02
Articles in Press
2016-09-28 18:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-02-08 10:42
Publish the Manuscript Online
2017-02-26 18:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title TGR5 expression in benign, preneoplastic and neoplastic lesions of Barrett’s esophagus: Case series and findings
Manuscript Source Unsolicited Manuscript
All Author List Shivali Marketkar, Dan Li, Dongfang Yang and Weibiao Cao
Funding Agency and Grant Number
Corresponding Author Weibiao Cao, MD, Department of Pathology, Rhode Island Hospital and Warren Alpert Medical School of Brown University, 593 Eddy St, APC12, Providence, RI 02903, United States. wcao@hotmail.com
Key Words TGR5; Esophageal adenocarcinoma; Bile acid
Core Tip The expression of a bile acid receptor TGR5 at moderate to strong intensity was significantly higher in high-grade dysplasia and esophageal adenocarcinoma (EA) cases than in BE or in low-grade dysplasia, suggesting that TGR5 may play an important role in the progression from Barrett’s esophagus to high-grade dysplasia and EA. TGR5 might be a potential marker for this progression. TGR5 staining intensity was not associated with the clinical stage, the pathological stage and the status of lymph node metastasis, indicating that TGR5 may not be a marker for the prognosis of EA.
Publish Date 2017-02-26 18:20
Citation Marketkar S, Li D, Yang D, Cao W. TGR5 expression in benign, preneoplastic and neoplastic lesions of Barrett’s esophagus: Case series and findings. World J Gastroenterol 2017; 23(8): 1338-1344
URL http://www.wjgnet.com/1007-9327/full/v23/i8/1338.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i8.1338
Full Article (PDF) WJG-23-1338.pdf
Full Article (Word) WJG-23-1338.doc
Manuscript File 28741-Review.doc
Answering Reviewers 28741-Answering reviewers.pdf
Audio Core Tip 28741-Audio core tip.mp3
Biostatistics Review Certificate 28741-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28741-Conflict-of-interest statement.pdf
Copyright License Agreement 28741-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 28741-Institutional review board statement.pdf
Peer-review Report 28741-Peer-review(s).pdf
Scientific Misconduct Check 28741-Scientific misconduct check.pdf
Scientific Editor Work List 28741-Scientific editor work list.pdf