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1/22/2017 11:39:00 AM | Browse: 835 | Download: 1569
Publication Name World Journal of Gastroenterology
Manuscript ID 28743
Country Colombia
Received
2016-07-13 09:46
Peer-Review Started
2016-07-17 21:49
To Make the First Decision
2016-08-19 10:54
Return for Revision
2016-08-23 11:01
Revised
2016-09-05 09:02
Second Decision
2016-09-09 17:44
Accepted by Journal Editor-in-Chief
2016-09-09 20:51
Accepted by Company Editor-in-Chief
2016-09-14 13:08
Articles in Press
2016-09-14 13:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-01-08 06:00
Typeset the Manuscript
2017-01-12 12:55
Publish the Manuscript Online
2017-01-22 11:39
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Basic Study
Article Title Genomic variability of Helicobacter pylori isolates of gastric regions from two Colombian populations
Manuscript Source Unsolicited Manuscript
All Author List Andrés Jenuer Matta, Alvaro Jairo Pazos, Javier Andrés Bustamante-Rengifo and Luis Eduardo Bravo
Funding Agency and Grant Number
Corresponding Author Andres Jenuer Matta, MSc, PhD, Registro Poblacional de Cáncer de Cali, Department of Pathology, School of Medicine, Universidad del Valle, Street 4B No. 36-00, Building 116, Floor 4, Cali 760043, Colombia. andres.matta@correounivalle.edu.co
Key Words Helicobacter pylori; Pathogenicity islet cag; cagA; vacA; Multiple colonization; PCR-RAPD
Core Tip Multiple colonization of Helicobacter pylori (H. pylori) occurred more frequently in individuals living in the Colombian population with higher risk of gastric cancer (GC) (Túquerres). In the two populations contrasted in relation to the risk of developing GC. (Túquerres high risk and Tumaco low risk) H. pylori was identified with specific genetic characteristics for each region and with varying stages of genomic variability. The diversity of H. pylori dependent of the anatomic regions of the gastric mucosa, obstructs the eradication of the microorganism. Identifying the multiple colonization and evaluating the genetic diversity of H. pylori individuals may be sifted that require particular schemes of early treatment and prevention of the precursor lesions of GC.
Publish Date 2017-01-22 11:39
Citation Matta AJ, Pazos AJ, Bustamante-Renjifo JA, Bravo LE. Genomic variability of Helicobacter pylori isolates of gastric regions from two Colombian populations. World J Gastroenterol 2017; 23(5): 800-809
URL http://www.wjgnet.com/1007-9327/full/v23/i5/800.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i5.800
Full Article (PDF) WJG-23-800.pdf
Full Article (Word) WJG-23-800.doc
Manuscript File 28743-Review.docx
Answering Reviewers 28743-Answering reviewers.pdf
Audio Core Tip 28743-Audio core tip.mp3
Biostatistics Review Certificate 28743-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28743-Conflict-of-interest statement.pdf
Copyright License Agreement 28743-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160713090732.docx
Institutional Review Board Approval Form or Document 28743-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 28743-Language certificate.pdf
Peer-review Report 28743-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 28743-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 28743-Scientific misconduct check.pdf
Scientific Editor Work List 28743-Scientific editor work list.pdf