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Articles Published Processes
9/15/2014 8:55:00 PM | Browse: 968 | Download: 1015
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Received |
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2013-03-22 09:26 |
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Peer-Review Started |
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2013-03-23 14:28 |
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To Make the First Decision |
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2013-04-16 09:01 |
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Return for Revision |
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2013-04-17 10:17 |
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Revised |
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Second Decision |
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2013-05-16 20:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-05-17 10:17 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-06-26 12:01 |
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Publish the Manuscript Online |
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2013-07-06 17:46 |
Category |
Surgery |
Manuscript Type |
Case Report |
Article Title |
Epstein-Barr virus negative primary hepatic leiomyoma: Case report and literature review
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Manuscript Source |
Invited Manuscript |
All Author List |
Xian-Zhang Luo, Chang-Sheng Ming, Xiao-Ping Chen and Nian-Qiao Gong |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81072441 (to Gong NG) |
National High-Tech Research and Development Program (Program 863) of the Ministry of Science and Technology of China |
2012AA021010 (to Ming CS) |
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Corresponding Author |
Nian-Qiao Gong, MD, PhD, Institute of Organ Transplantation, Department of Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue,Wuhan 430030, Hubei Province, China. nqgong@tjh.tjmu.edu.cn |
Key Words |
Epstein-Barr virus; Primary hepatic leiomyoma; Cancer diagnosis; Tumor resection; Developmental biology |
Core Tip |
Primary hepatic leiomyoma is usually found in adult women and is associated with Epstein-Barr virus (EBV) infection. We report the 29th case worldwide in a 48-year-old kidney allograft recipient without EBV infection and extrahepatic tumor. He achieved clinical cure by mass resection. The leiomyoma was positive for α-smooth muscle actin and desmin, and negative for gastrointestinal stromal tumor markers, including CD117, CD34 and DOG1 (discovered on gastrointestinal stromal tumor 1). The tumor was negative for EBV-encoded small RNA. The data indicate that EBV infection is important but neither necessary nor sufficient for development of primary liver leiomyoma. |
Publish Date |
2013-07-06 17:46 |
Citation |
Luo XZ, Ming CS, Chen XP, Gong NQ. Epstein-Barr virus negative primary hepatic leiomyoma: Case report and literature review. World J Gastroenterol 2013; 19(25): 4094-4098 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i25/4094.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i25.4094 |
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