Publication Name	World Journal of Gastroenterology
Manuscript ID	28894
Country	Canada

Received	2016-07-20 15:06
Peer-Review Started	2016-07-21 18:42
To Make the First Decision	2016-08-22 15:09
Return for Revision	2016-08-23 09:03
Revised	2016-09-15 00:46
Second Decision	2016-09-30 17:38
Accepted by Journal Editor-in-Chief	2016-09-30 19:00
Accepted by Executive Editor-in-Chief	2016-10-10 17:41
Articles in Press	2016-10-10 17:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-17 21:06
Publish the Manuscript Online	2016-12-26 19:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Effects of Saccharomyces cerevisiae or boulardii yeasts on acute stress induced intestinal dysmotility
Manuscript Source	Invited Manuscript
All Author List	Christine West, Andrew M Stanisz, Annette Wong and Wolfgang A Kunze
Funding Agency and Grant Number	Funding Agency Grant Number Natural Sciences and Engineering Research Council of Canada Discovery Grant 2014-05517
Corresponding Author	Christine West, MSc Candidate, BSc, McMaster Brain-Body Institute, St. Joseph’s Healthcare, Hamilton, 50 Charlton Street East, ON L8N 4A6, Canada. westcl2@mcmaster.ca
Key Words	Intestine; Saccharomyces cerevisiae; Saccharomyces boulardii; Restraint stress; Motility
Core Tip	The use of Saccharomyces cerevisiae and Saccharomyces boulardii yeasts as therapeutic agents were tested for their ability to reverse the intestinal discomfort caused by acute stress. Most studies investigate the role of microbes in the prevention of stress, however the yeasts showed promising acute therapeutic effects for the treatment of stress. Additionally, the residual supernatant (Snt) after centrifugation of the yeasts was able to recapitulate much of the effect of the microbes themselves. Saccharomyces yeasts or Snt may be potential probiotic therapies in the treatment of acute stress-related intestinal dysmotility.
Publish Date	2016-12-26 19:13
Citation	West C, Stanisz AM, Wong A, Kunze WA. Effects of Saccharomyces cerevisiae or boulardii yeasts on acute stress induced intestinal dysmotility. World J Gastroenterol 2016; 22(48): 10532-10544
URL	http://www.wjgnet.com/1007-9327/full/v22/i48/10532.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i48.10532

Full Article (PDF)	WJG-22-10532.pdf
Full Article (Word)	WJG-22-10532.doc
Manuscript File	28894-Review.docx
Answering Reviewers	28894-Answering reviewers.pdf
Audio Core Tip	28894-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	28894-Conflict-of-interest statement.pdf
Copyright License Agreement	28894-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	Institutional_Animal_Care_and_Use_Committee_Statement_20160720003003.pdf
Peer-review Report	28894-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	28894-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	28894-Scientific misconduct check.pdf
Scientific Editor Work List	28894-Scientific editor work list.pdf