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11/12/2016 1:33:00 PM | Browse: 297 | Download: 224
Publication Name World Journal of Gastroenterology
Manuscript ID 28897
Country of Manuscript Source Japan
2016-07-20 14:45
Peer-Review Started
2016-07-22 10:21
To Make the First Decision
2016-07-29 15:15
Return for Revision
2016-07-29 19:16
2016-08-11 02:33
Second Decision
2016-08-17 08:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-08-23 17:35
Articles in Press
2016-08-23 17:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-11-04 14:58
Publish the Manuscript Online
2016-11-12 13:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Case Report
Article Title Complete response with sorafenib and transcatheter arterial chemoembolization in unresectable hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Michitoshi Takano, Takashi Kokudo, Yoshihiro Miyazaki, Yumiko Kageyama, Amane Takahashi, Katsumi Amikura and Hirohiko Sakamoto
Funding Agency and Grant Number
Correspondence To Michitoshi Takano, MD, Division of gastroenterological surgery, Saitama Cancer Center, 780 Komuro, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan. michitaka1983@gmail.com
Keywords Hepatocellular carcinoma; Sorafenib; Complete response; Portal vein tumor thrombosis; Transcatheter arterial chemoembolization
Core Tip Patients with advanced hepatocellular carcinoma (HCC) showing portal vein tumor thrombosis (PVTT) have an extremely poor prognosis. The only proposed treatment option for HCC patients with PVTT is sorafenib chemotherapy. However, in Asia, various treatments have been attempted and possible prolongation of overall survival has been repeatedly reported. Here we report the first case of a patient with an initially unresectable advanced HCC and PVTT who underwent curative hepatectomy after sorafenib and transcatheter arterial chemoembolization (TACE) showing complete histological response. The combination of sorafenib and TACE may be an effective treatment for HCC patients with PVTT.
Publish Date 2016-11-12 13:34
Citation Takano M, Kokudo T, Miyazaki Y, Kageyama Y, Takahashi A, Amikura K, Sakamoto H. Complete response with sorafenib and transcatheter arterial chemoembolization in unresectable hepatocellular carcinoma. World J Gastroenterol 2016; 22(42): 9445-9450
Url http://www.wjgnet.com/1007-9327/full/v22/i42/9445.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i42.9445
Full Article (PDF) WJG-22-9445.pdf
Full Article (Word) WJG-22-9445.doc
Revised Manuscript 28897-Review.docx
Peer-review Report 28897-Peer-review(s).pdf
Answering Reviewers 28897-Answering reviewers.pdf
Scientific Misconduct Check 28897-Scientific misconduct check.pdf
Scientific Editor Work List 28897-Scientific editor work list.pdf
Audio Core Tip 28897-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 28897-Conflict-of-interest statement.pdf
Copyright License Agreement 28897-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 28897-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 28897-Language certificate.pdf