Publication Name	World Journal of Gastroenterology
Manuscript ID	2895
Country	China

Received	2013-03-22 11:20
Peer-Review Started	2013-03-24 09:02
To Make the First Decision	2013-04-03 09:11
Return for Revision	2013-04-15 18:41
Revised	2013-04-25 17:27
Second Decision	2013-06-03 16:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-06-04 09:41
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-06-28 10:40
Typeset the Manuscript	2013-07-18 16:48
Publish the Manuscript Online	2013-07-29 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Efficacy of capecitabine and oxaliplatin regimen for extrahepatic metastasis of hepatocellular carcinoma following local treatments
Manuscript Source	Invited Manuscript
All Author List	Sheng-Li He, Jie Shen, Xian-Jun Sun, Xiao-Juan Zhu, Lu-Ming Liu and Jing-Cheng Dong
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Municipal Health Bureau Outstanding Young Clinical Personal Training Project ZYSNXD-YL-YSZK025
Corresponding Author	Dr. Sheng-Li He, Department of Hepato-Biliary and Pancreatic Oncology, Fudan University Shanghai Cancer Center, Minhang Branch, Shanghai 200240, China. hlshli@yeah.net
Key Words	Hepatocellular carcinoma; Extrahepatic metastasis; Capecitabine; Oxaliplatin; Local treatments
Core Tip	Distant metastases are still obstacles in improvement of outcome in hepatocellular carcinoma (HCC) patients after local treatment. Although, sorafenib is used as a standard systemic treatment for those patients, it is not suitable for patients with intermediate HCC who were not eligible to or failed in the locoregional therapy. This study reports the capecitabine and oxaliplatin regimen for extrahepatic metastasis after local treatment of HCC. The objective response rate was 21.9%, and 40.6% of patients had stable disease, and the median overall survival and the time to tumor progression were 4.2 and 9.2 mo, respectively. Furthermore, the result of this study showed that toxicity profile was tolerated well.
Publish Date	2013-07-29 11:18
Citation	He SL, Shen J, Sun XJ, Zhu XJ, Liu LM, Dong JC. Efficacy of capecitabine and oxaliplatin regimen for extrahepatic metastasis of hepatocellular carcinoma following local treatments. World J Gastroenterol 2013; 19(28): 4552-4558
URL	http://www.wjgnet.com/1007-9327/full/v19/i28/4552.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i28.4552

Full Article (PDF)	WJG-19-4552.pdf
Manuscript File	2895-Review.doc
Answering Reviewers	2895-Answering reviewers.pdf
Copyright License Agreement	2895-Copyright assignment.pdf
Peer-review Report	2895-Peer reviews.pdf
Scientific Editor Work List	2895-Scientific editor work list.doc