Publication Name	World Journal of Orthopedics
Manuscript ID	28966
Country	Switzerland

Received	2016-07-24 18:28
Peer-Review Started	2016-07-26 09:42
To Make the First Decision	2016-09-05 09:18
Return for Revision	2016-09-06 08:42
Revised	2016-09-19 01:08
Second Decision	2016-09-28 11:29
Accepted by Journal Editor-in-Chief	2016-09-29 10:40
Accepted by Executive Editor-in-Chief	2016-10-18 16:39
Articles in Press	2016-10-18 16:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-29 13:59
Publish the Manuscript Online	2017-01-10 16:10

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Frontier
Article Title	Glucosamine and chondroitin for the treatment of osteoarthritis
Manuscript Source	Invited Manuscript
All Author List	Haris S Vasiliadis and Konstantinos Tsikopoulos
Funding Agency and Grant Number
Corresponding Author	Haris S Vasiliadis, MD, PhD, Ortho­paedie Sonnenhof, Buchserstrasse 30, 3006 Bern, Switzerland. vasiliadismd@gmail.com
Key Words	Glucosamine; Chondroitin; Osteoarthritis; Knee; Cartilage
Core Tip	In this review we present and critically evaluate the current information regarding the admini-stration of glucosamine (GL) and chondroitin (CH) for the treatment of knee or hip osteoarthritis. A clinical and radiological effect of GL and CH has been shown. However, only a few high quality trials exist. The effect sizes are small and probably not clinically relevant. The validity of these results is limited by high risk of bias introduced in the studies. Both GL and CH seem to be safe with no serious adverse events but there is currently no convincing information for their efficacy as treatment options in osteoarthritis.
Publish Date	2017-01-10 16:10
Citation	Vasiliadis HS, Tsikopoulos K. Glucosamine and chondroitin for the treatment of osteoarthritis. World J Orthop 2017; 8(1): 1-11
URL	http://www.wjgnet.com/2218-5836/full/v8/i1/1.htm
DOI	http://dx.doi.org/10.5312/wjo.v8.i1.1

Full Article (PDF)	WJO-8-1.pdf
Full Article (Word)	WJO-8-1.doc
Manuscript File	28966-Review.docx
Answering Reviewers	28966-Answering reviewers.pdf
Audio Core Tip	28966-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	28966-Conflict-of-interest statement.pdf
Copyright License Agreement	28966-Copyright assignment.pdf
Peer-review Report	28966-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	28966-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	28966-Scientific misconduct check.pdf
Scientific Editor Work List	28966-Scientific editor work list.pdf