Publication Name	World Journal of Gastroenterology
Manuscript ID	2901
Country	South Korea

Received	2013-03-23 22:51
Peer-Review Started	2013-03-24 18:39
To Make the First Decision	2013-04-16 08:59
Return for Revision	2013-04-17 10:46
Revised	2013-05-15 17:41
Second Decision	2013-06-03 16:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-06-04 09:51
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-24 21:04
Publish the Manuscript Online	2013-08-06 09:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Nutrition & Dietetics
Manuscript Type	Autobiography
Article Title	Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation
Manuscript Source	Invited Manuscript
All Author List	Young-Je Kim, Myung-Sook Choi, Yong Bok Park, Sang Ryong Kim, Mi-Kyung Lee and Un Ju Jung
Funding Agency and Grant Number	Funding Agency Grant Number Basic Science Research Program 2011-0022387 SRC program, Center for Food and Nutritional Genomics from National Research Foundation of Korea funded by the Ministry of Education, Science and Technology 2012-0000644
Corresponding Author	Un Ju Jung, PhD, Center for Food and Nutritional Genomics Research, Kyungpook National University, 1370 San-Kyuk Dong, Puk-Ku, Daegu 702-701, South Korea. jungunju@naver.com
Key Words	Garcinia Cambogia; Anti-adiposity; Metabolic changes; Hepatic collagen accumulation; Hepatic inflammation; Hepatic oxidative stress
Core Tip	Garcinia Cambogia (GC) is a popular dietary supplement for weight loss. However, little is known about the efficacy and hepatotoxicity of long-term GC supplementation in mice fed a high-fat diet (HFD). We observed that GC ameliorated HFD-induced adiposity by modulating enzymatic activity and gene expression involved in fatty acid metabolism. GC also reduced the plasma resistin level and glucose intolerance. However, GC caused hepatic collagen accumulation, inflammation and oxidative stress without affecting hepatic steatosis.
Publish Date	2013-08-06 09:19
Citation	Kim YJ, Choi MS, Park YB, Kim SR, Lee MK, Jung UJ. Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation. World J Gastroenterol 2013; 19(29): 4689-4701
URL	http://www.wjgnet.com/1007-9327/full/v19/i29/4689.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i29.4689

Full Article (PDF)	WJG-19-4689.pdf
Manuscript File	2901-Review.doc
Answering Reviewers	2901-Answering reviewers.pdf
Copyright License Agreement	2901-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	ethics committee approval document.doc
Non-Native Speakers of English Editing Certificate	2901-Language certificate.pdf
Peer-review Report	2901-Peer reviews.pdf
Scientific Editor Work List	2901-Scientific editor work list.doc