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Articles Published Processes
11/6/2016 3:43:00 PM | Browse: 1097 | Download: 2097
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Received |
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2016-08-10 11:25 |
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Peer-Review Started |
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2016-08-11 10:07 |
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To Make the First Decision |
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2016-09-12 17:01 |
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Return for Revision |
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2016-09-14 16:11 |
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Revised |
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2016-09-27 06:42 |
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Second Decision |
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2016-10-10 13:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-10-19 17:17 |
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Articles in Press |
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2016-10-19 17:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-11-04 08:57 |
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Publish the Manuscript Online |
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2016-11-06 15:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Denise E Brennan, Joseph Omorogbe, Mary Hussey, Donal Tighe, Grainne Holleran, Colm O’Morain, Sinéad M Smith and Deirdre McNamara |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Sinéad M Smith, PhD, Assistant Professor, Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Tallaght, Dublin 2,
Ireland. smithsi@tcd.ie
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| Key Words |
Helicobacter pylori; Antibiotic resistance; Clarithromycin; Fluoroquinolone; Molecular methods |
| Core Tip |
The successful detection of clarithromycin and/or fluoroquinolone resistant Helicobacter pylori (H. pylori) infections by non-invasive methods would enable a widespread assessment of resistance rates. Here we evaluate the GenoType HelicoDR assay for the detection of clarithromycin and fluoroquinolone resistance using DNA isolated from stool samples compared to biopsy samples. Although results using this assay on biopsy tissue have previously been shown to correspond well with culture and antimicrobial susceptibility testing, there was weak correlation between results obtained using biopsy vs stool samples in our study. Further studies are required to optimise the non-invasive detection of clarithromycin and fluoroquinolone resistant H. pylori infection.
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| Publish Date |
2016-11-06 15:43 |
| Citation |
Brennan DE, Omorogbe J, Hussey M, Tighe D, Holleran G, O’Morain C, Smith SM, McNamara D. Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples. World J Gastroenterol 2016; 22(41): 9214-9221 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i41/9214.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i41.9214 |
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