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3/19/2017 6:44:00 PM | Browse: 306 | Download: 293
Publication Name World Journal of Gastroenterology
Manuscript ID 29259
Country/Territory United States
Received
2016-08-04 17:30
Peer-Review Started
2016-08-05 13:21
To Make the First Decision
2016-11-21 08:42
Return for Revision
2016-11-23 17:01
Revised
2016-12-02 11:56
Second Decision
2017-01-06 13:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-01-11 12:04
Articles in Press
2017-01-11 12:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-03-10 10:53
Publish the Manuscript Online
2017-03-19 18:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Clinical translation of bioartificial liver support systems with human pluripotent stem cell-derived hepatic cells
Manuscript Source Unsolicited Manuscript
All Author List Ryoichi Sakiyama, Brandon J Blau and Toshio Miki
Funding Agency and Grant Number
Funding Agency Grant Number
Baxter International Foundation/Keck Summer Research Fellowship Award to Blau BJ
California Institute for Regenerative Medicine RT3-07670
Corresponding author Toshio Miki, MD, PhD, Assistant Professor of Research, Department of Surgery, Keck School of Medicine, University of Southern California 2011 Zonal Avenue, HMR 509A, Los Angeles, CA 90033, United States. toshiomi@usc.edu
Keywords Artificial liver; Clinical trial; Hepatocytes; Pluripotent stem cells; Bioreactors
Core Tip The current lack of transplantable donor livers in the world has led to the development of extracorporeal liver support systems as one possible approach to overcome this problem. Bioartificial liver (BAL) support systems require a cell source to replicate human liver function, yet the ideal cell source for this purpose has yet to be determined. Highly-functional hepatocyte-like cells have recently been generated from human pluripotent stem cells, which show promise as a potential cell source in BAL support systems for the treatment of liver failure in the future.
Publish Date 2017-03-19 18:45
Citation Sakiyama R, Blau BJ, Miki T. Clinical translation of bioartificial liver support systems with human pluripotent stem cell-derived hepatic cells. World J Gastroenterol 2017; 23(11): 1974-1979
Url http://www.wjgnet.com/1007-9327/full/v23/i11/1974.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i11.1974
Full Article (PDF) WJG-23-1974.pdf
Full Article (Word) WJG-23-1974.doc
Manuscript File 29259-Review.docx
Answering Reviewers 29259-Answering reviewers.pdf
Audio Core Tip 29259-Audio core tip.wav
Conflict-of-Interest Disclosure Form 29259-Conflict-of-interest statement.PDF
Copyright License Agreement 29259-Copyright assignment.PDF
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 29259-Grant application form(s).pdf
Peer-review Report 29259-Peer-review(s).pdf
Scientific Misconduct Check 29259-Scientific misconduct check.pdf
Scientific Editor Work List 29259-Scientific editor work list.pdf