Publication Name	World Journal of Gastroenterology
Manuscript ID	2940
Country	Ireland

Received	2013-03-27 09:11
Peer-Review Started	2013-03-28 08:44
To Make the First Decision	2013-04-03 09:17
Return for Revision	2013-04-12 11:08
Revised	2013-04-22 23:21
Second Decision	2013-05-18 17:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-05-20 00:06
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-14 09:39
Publish the Manuscript Online	2013-08-27 16:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	MicroRNAs and liver cancer associated with iron overload: Therapeutic targets unravelled
Manuscript Source	Invited Manuscript
All Author List	Catherine M Greene, Robert B Varley and Matthew W Lawless
Funding Agency and Grant Number
Corresponding Author	Matthew W Lawless, BSc, MSc, PhD, Experimental Medicine, UCD School of Medicine and Medical Science, Mater Misericordiae University Hospital, Catherine McAuley Centre, Nelson Street, Dublin 7, Ireland. matthew.lawless@ucd.ie
Key Words	MicroRNAs; Liver cancer; Iron regulation; Hepatitis C; Therapeutic targets
Core Tip	Hepatocellular carcinoma (HCC) has a high incidence and low survival rate, largely attributable to late diagnosis, resistance to treatment, tumour recurrence and metastasis. MicroRNAs (miRNAs) are regulatory RNAs that modulate protein synthesis and are involved in several biological and pathological processes including the development and progression of HCC. miRNAs represent important new targets for therapeutic intervention for HCC and have potential as diagnostic and prognostic HCC biomarkers. Ongoing studies and clinical trials suggest miRNA-based treatments and diagnostic methods will have clinical applications for HCC in the coming years, yielding improved HCC survival rates and patient outcomes.
Publish Date	2013-08-27 16:46
Citation	Greene CM, Varley RB, Lawless MW. MicroRNAs and liver cancer associated with iron overload: Therapeutic targets unravelled. World J Gastroenterol 2013; 19(32): 5212-5226
URL	http://www.wjgnet.com/1007-9327/full/v19/i32/5212.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i32.5212

Full Article (PDF)	WJG-19-5212.pdf
Manuscript File	2940-Review.docx
Answering Reviewers	2940-Answering reviewers.doc
Copyright License Agreement	2940-Copyright assignment.pdf
Peer-review Report	2940-Peer review(s).pdf
Scientific Editor Work List	2940-Scientific editor work list.doc