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Publication Name World Journal of Gastroenterology
Manuscript ID 2940
Country/Territory Ireland
2013-03-27 09:11
Peer-Review Started
2013-03-28 08:44
To Make the First Decision
2013-04-03 09:17
Return for Revision
2013-04-12 11:08
2013-04-22 23:21
Second Decision
2013-05-18 17:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-05-20 00:06
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-08-14 09:39
Publish the Manuscript Online
2013-08-27 16:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title MicroRNAs and liver cancer associated with iron overload: Therapeutic targets unravelled
Manuscript Source Invited Manuscript
All Author List Catherine M Greene, Robert B Varley and Matthew W Lawless
Funding Agency and Grant Number
Corresponding author Matthew W Lawless, BSc, MSc, PhD, Experimental Medicine, UCD School of Medicine and Medical Science, Mater Misericordiae University Hospital, Catherine McAuley Centre, Nelson Street, Dublin 7, Ireland. matthew.lawless@ucd.ie
Keywords MicroRNAs; Liver cancer; Iron regulation; Hepatitis C; Therapeutic targets
Core Tip Hepatocellular carcinoma (HCC) has a high incidence and low survival rate, largely attributable to late diagnosis, resistance to treatment, tumour recurrence and metastasis. MicroRNAs (miRNAs) are regulatory RNAs that modulate protein synthesis and are involved in several biological and pathological processes including the development and progression of HCC. miRNAs represent important new targets for therapeutic intervention for HCC and have potential as diagnostic and prognostic HCC biomarkers. Ongoing studies and clinical trials suggest miRNA-based treatments and diagnostic methods will have clinical applications for HCC in the coming years, yielding improved HCC survival rates and patient outcomes.
Publish Date 2013-08-27 16:46
Citation Greene CM, Varley RB, Lawless MW. MicroRNAs and liver cancer associated with iron overload: Therapeutic targets unravelled. World J Gastroenterol 2013; 19(32): 5212-5226
Url http://www.wjgnet.com/1007-9327/full/v19/i32/5212.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i32.5212
Full Article (PDF) WJG-19-5212.pdf
Manuscript File 2940-Review.docx
Answering Reviewers 2940-Answering reviewers.doc
Copyright License Agreement 2940-Copyright assignment.pdf
Peer-review Report 2940-Peer review(s).pdf
Scientific Editor Work List 2940-Scientific editor work list.doc