Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	29461
Country	Japan

Received	2016-08-15 16:57
Peer-Review Started	2016-08-16 18:11
First Decision by Editorial Office Director
Return for Revision	2016-09-28 09:12
Revised	2016-10-08 13:41
Publication Fee Transferred
Second Decision by Editor	2016-10-28 11:28
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2016-11-02 16:20
Articles in Press	2016-11-02 16:20
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-28 20:32
Publish the Manuscript Online	2017-01-12 12:07

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Novel therapeutic approaches targeting L-type amino acid transporters for cancer treatment
Manuscript Source	Invited Manuscript
All Author List	Keitaro Hayashi and Naohiko Anzai
Funding Agency and Grant Number
Corresponding Author	Keitaro Hayashi, PhD, Associate Professor, Department of Pharmacology and Toxicology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321-0293, Japan. khayashi@dokkyomed.ac.jp
Key Words	LAT1; Amino acid transporter; Molecular target drug; Amino acid starvation response; Signal transduction
Core Tip	The discovery of molecules preferentially expressed in cancer cells is extremely valuable for the development of molecular target drugs in cancer therapy. Amino acid transporters have been receiving a great amount of attention as a candidate of such molecular targets. This review summarizes new initiatives for clinical applications of the basic research relative to L-type amino acid transporters, which are commonly expressed in cancers.
Publish Date	2017-01-12 12:07
Citation	Hayashi K, Anzai N. Novel therapeutic approaches targeting L-type amino acid transporters for cancer treatment. World J Gastrointest Oncol 2017; 9(1): 21-29
URL	http://www.wjgnet.com/1948-5204/full/v9/i1/21.htm
DOI	http://dx.doi.org/10.4251/wjgo.v9.i1.21

Full Article (PDF)	WJGO-9-21.pdf
Full Article (Word)	WJGO-9-21.doc
Manuscript File	29461-Review.docx
Answering Reviewers	29461-Answering reviewers.pdf
Audio Core Tip	29461-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29461-Conflict-of-interest statement.pdf
Copyright License Agreement	29461-Copyright assignment.pdf
Peer-review Report	29461-Peer-review(s).pdf
Scientific Misconduct Check	29461-Scientific misconduct check.pdf
Scientific Editor Work List	29461-Scientific editor work list.pdf