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        12/13/2016 12:40:00 AM | Browse: 1072 | Download: 1884
    
    
        
        
    
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                    |  | Received |  | 2016-08-24 10:47 | 
    
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                    |  | Peer-Review Started |  | 2016-08-25 15:04 | 
    
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                    |  | To Make the First Decision |  | 2016-09-05 14:17 | 
    
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                    |  | Return for Revision |  | 2016-09-07 10:53 | 
    
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                    |  | Revised |  | 2016-09-23 18:17 | 
    
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                    |  | Second Decision |  | 2016-10-25 20:02 | 
    
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                    |  | Accepted by Journal Editor-in-Chief |  | 2016-10-26 15:09 | 
    
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                    |  | Accepted by Executive Editor-in-Chief |  | 2016-10-31 15:05 | 
    
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                    |  | Articles in Press |  | 2016-10-31 15:05 | 
    
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                    |  | Publication Fee Transferred |  |  | 
    
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                    |  | Edit the Manuscript by Language Editor |  |  | 
    
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                    |  | Typeset the Manuscript |  | 2016-12-02 14:11 | 
            
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                            |  | Publish the Manuscript Online |  | 2016-12-13 00:40 | 
        
        
            
                | ISSN | 1007-9327 (print) and 2219-2840 (online) | 
            
                | Open Access | This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ | 
            
                | Copyright | © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. | 
                    
                        | Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 | 
            
            
                | Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 | 
            
            
                | Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA | 
            
                | Website | http://www.wjgnet.com | 
        
    
        | Category | Oncology | 
    
        | Manuscript Type | Minireviews | 
    
        | Article Title | Dilemma of first line regimens in metastatic pancreatic adenocarcinoma | 
    
        | Manuscript Source | Invited Manuscript | 
    
        | All Author List | Marwan Ghosn, Tony Ibrahim, Tarek Assi, Elie El Rassy, Hampig Raphael Kourie and Joseph Kattan | 
    
        | Funding Agency and Grant Number |  | 
    
        | Corresponding Author | Marwan Ghosn, MD, Department of Oncology, Faculty of Medicine, Saint Joseph University, Alfred Naccache, Beirut 166830, Lebanon. marwanghosnmd@yahoo.com | 
    
        | Key Words | Review; Metastatic pancreatic cancer; FOLFIRINOX; Gemcitabine/nab-paclitaxel; Pivotal trials | 
    
        | Core Tip | This paper is a mini-review that compares the design of the two pivotal trials studying the role of FOLFIRINOX and gemcitabine/nab-Paclitaxel in the management of metastatic pancreatic cancer. It also analyzes the effects these regimens have on toxicity profile, quality of life, real life experiences, choice of second-line therapy and cost. | 
            
                | Publish Date | 2016-12-13 00:40 | 
    
        | Citation | Ghosn M, Ibrahim T, Assi T, El Rassy E, Kourie HR, Kattan J. dilemma of first line regimens in metastatic pancreatic adenocarcinoma. World J Gastroenterol 2016; 22(46): 10124-10130 | 
            
                | URL | http://www.wjgnet.com/1007-9327/full/v22/i46/10124.htm | 
            
                | DOI | http://dx.doi.org/10.3748/wjg.v22.i46.10124 | 
    
    
        
                
        
     
 
                 
             
         
        
    
        
        
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