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2/25/2017 3:11:00 PM | Browse: 1245 | Download: 1347
Publication Name World Journal of Biological Chemistry
Manuscript ID 29651
Country Italy
Received
2016-08-24 09:45
Peer-Review Started
2016-08-24 15:18
To Make the First Decision
2016-09-27 17:15
Return for Revision
2016-10-08 11:22
Revised
2016-10-20 00:33
Second Decision
2017-01-10 17:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-01-18 10:17
Articles in Press
2017-01-18 10:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-02-20 08:31
Publish the Manuscript Online
2017-02-25 15:11
ISSN 1949-8454 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Review
Article Title Role of microRNAs in translation regulation and cancer
Manuscript Source Invited Manuscript
All Author List Stefania Oliveto, Marilena Mancino, Nicola Manfrini and Stefano Biffo
Funding Agency and Grant Number
Funding Agency Grant Number
Fondazione BUZZI Unicem
Corresponding Author Stefano Biffo, PhD, Program Leader of INGM, Professor of Cell Biology and Comparative Anatomy, Department of Biosciences, University of Milan, Piazza dell’Ateneo Nuovo 1, 20133 Milano, Italy. biffo@ingm.org
Key Words MicroRNA; Translation; Cancer; OncomiR; Tumor suppressor
Core Tip MicroRNAs (miRNAs) are short non-coding RNAs (19-25 bp in length) which negatively regulate gene expression at the mRNA and protein level. By binding coding transcripts, miRNAs cause degradation or trans-lation inhibition of their target genes and affect a multi-tude of biological processes, such as proliferation and tumor growth. In this review we critically analyze the mechanism of action of miRNAs and their potential role in cancer, opening a window on future perspectives for their use as novel therapeutic targets.
Publish Date 2017-02-25 15:11
Citation Oliveto S, Mancino M, Manfrini N, Biffo S. Role of microRNAs in translation regulation and cancer. World J Biol Chem 2017; 8(1): 45-56
URL http://www.wjgnet.com/1949-8454/full/v8/i1/45.htm
DOI http://dx.doi.org/10.4331/wjbc.v8.i1.45
Full Article (PDF) WJBC-8-45.pdf
Full Article (Word) WJBC-8-45.doc
Manuscript File 29651-Review.docx
Answering Reviewers 29651-Answering reviewers.pdf
Audio Core Tip 29651-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 29651-Conflict-of-interest statement.pdf
Copyright License Agreement 29651-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 29651-Grant application form(s).pdf
Peer-review Report 29651-Peer-review(s).pdf
Scientific Misconduct Check 29651-Scientific misconduct check.pdf
Scientific Editor Work List 29651-Scientific editor work list.pdf