Publication Name	World Journal of Hepatology
Manuscript ID	29702
Country	Serbia

Received	2016-08-25 09:06
Peer-Review Started	2016-08-26 15:22
To Make the First Decision	2016-11-11 08:58
Return for Revision	2016-11-19 20:05
Revised	2016-12-03 00:37
Second Decision	2017-03-07 15:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-03-17 14:03
Articles in Press	2017-03-17 14:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-29 11:40
Publish the Manuscript Online	2017-04-05 15:41

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Drug-induced liver injury: Do we know everything?
Manuscript Source	Invited Manuscript
All Author List	Tamara Alempijevic, Simon Zec and Tomica Milosavljevic
Funding Agency and Grant Number
Corresponding Author	Tamara Alempijevic, MD, PhD, Pro­fessor, University of Belgrade, School of Medicine, 2 Dr Koste Todorovica Street, 11000 Belgrade, Serbia. tamara.alempijevic@med.bg.ac.rs
Key Words	Acute liver failure; Drug-induced liver injury; Hepatoxicity; Acetaminophen toxicity; Cholestatic injury; Liver biopsy; Pharmacoepidemiology; Herbal-induced liver injury; Hy’s law
Core Tip	Drug-induced liver injury has gained a great amount of interest in the past decade, raising the question of whether we know everything. Various global registries have been established and the first guidelines for diagnosis and management have come to define the state of the art. The identification of risk factors and predictors of injury, novel mechanisms of injury, refined causality assessment tools, and targeted treatment options have amplified our understanding of the impact of drug-induced liver injury, however gaps in our know­ledge still remain.
Publish Date	2017-04-05 15:41
Citation	Alempijevic T, Zec S, Milosavljevic T. Drug-induced liver injury: Do we know everything? World J Hepatol 2017; 9(10): 491-502
URL	http://www.wjgnet.com/1948-5182/full/v9/i10/491.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i10.491

Full Article (PDF)	WJH-9-491.pdf
Full Article (Word)	WJH-9-491.doc
Manuscript File	29702-Review.docx
Answering Reviewers	29702-Answering reviewers.pdf
Audio Core Tip	29702-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29702-Conflict-of-interest statement.pdf
Copyright License Agreement	29702-Copyright assignment.pdf
Peer-review Report	29702-Peer-review(s).pdf
Scientific Misconduct Check	29702-Scientific misconduct check.pdf
Scientific Editor Work List	29702-Scientific editor work list.pdf