Publication Name	World Journal of Transplantation
Manuscript ID	29706
Country	United States

Received	2016-08-25 11:26
Peer-Review Started	2016-08-26 15:40
To Make the First Decision	2016-10-20 08:41
Return for Revision	2016-10-28 11:35
Revised	2016-11-16 01:24
Second Decision	2017-01-23 12:51
Accepted by Journal Editor-in-Chief	2017-01-24 19:17
Accepted by Executive Editor-in-Chief	2017-02-13 13:42
Articles in Press	2017-02-13 13:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-04-13 14:13
Publish the Manuscript Online	2017-04-20 20:08

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Transplantation
Manuscript Type	Review
Article Title	Role of gastroesophageal reflux disease in lung transplantation
Manuscript Source	Invited Manuscript
All Author List	Kelly E Hathorn, Walter W Chan and Wai-Kit Lo
Funding Agency and Grant Number
Corresponding Author	Walter W Chan, MD, MPH, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, United States. wwchan@partners.org
Key Words	Lung transplant; Reflux; Aspiration; Rejection; Bronchiolitis obliterans syndrome; Fundoplication
Core Tip	Gastroesophageal reflux disease (GERD) has been associated with increased morbidity in lung transplant patients through a proposed pathway of reflux, aspiration, immunomodulation, and allograft injury, culminating in functional decline and rejection. This paper reviews the mechanisms of GERD-induced injury, describes outcome measures important in post-transplant assessment, and discusses the timing and modalities of diagnostic evaluation and management, including medical and surgical antireflux treatment, in optimizing post-transplant outcomes. A greater awareness of the harmful effects of GERD in the lung transplant population is important in the early diagnosis and management of such patients to minimize allograft injury and improve outcomes.
Publish Date	2017-04-20 20:08
Citation	Hathorn KE, Chan WW, Lo WK. Role of gastroesophageal reflux disease in lung transplantation. World J Transplant 2017; 7(2): 103-116
URL	http://www.wjgnet.com/2220-3230/full/v7/i2/103.htm
DOI	http://dx.doi.org/10.5500/wjt.v7.i2.103

Full Article (PDF)	WJT-7-103.pdf
Full Article (Word)	WJT-7-103.doc
Manuscript File	29706-Review.docx
Answering Reviewers	29706-Answering reviewers.pdf
Audio Core Tip	29706-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	29706-Conflict-of-interest statement.pdf
Copyright License Agreement	29706-Copyright assignment.pdf
Peer-review Report	29706-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	29706-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	29706-Scientific misconduct check.pdf
Scientific Editor Work List	29706-Scientific editor work list.pdf