| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Potential application of neogalactosylalbumin in positron emission tomography evaluation of liver function
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shun-Da Du, Shao-Hua Li, Bao Jin, Zhao-Hui Zhu, Yong-Hong Dang, Hai-Qun Xing, Fang Li, Xue-Bing Wang, Xin Lu, Xin-Ting Sang, Hua-Yu Yang, Shou-Xian Zhong and Yi-Lei Mao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
30901453 |
| National Natural Science Foundation of China |
81201566 |
| National Key Technology Research and Development Program of China |
BAI06B01 |
| Youth Grant of Peking Union Medical College Hospital |
|
|
| Corresponding Author |
Yi-Lei Mao, MD, PhD, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuai-Fu-Yuan, Wangfujing, Beijing 100730, China. yileimao@126.com |
| Key Words |
Neogalactosylalbumin; Positron emission tomography; Liver function; Liver fibrosis; Mouse model |
| Core Tip |
Neogalactosylalbumin (NGA) is a specific ligand for asialoglycoprotein receptor that is exclusively expressed on the surface of hepatic parenchymal cells. This study showed [18F]FNGA mainly accumulated in liver and remained for sufficient time. Functionally-impaired liver showed a significant different uptake pattern of [18F]FNGA compared to controls. |
| Publish Date |
2017-06-20 12:12 |
| Citation |
Du SD, Li SH, Jin B, Zhu ZH, Dang YH, Xing HQ, Li F, Wang XB, Lu X, Sang XT, Yang HY, Zhong SX, Mao YL. Potential application of neogalactosylalbumin in positron emission tomography evaluation of liver function. World J Gastroenterol 2017; 23(23): 4278-4284 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i23/4278.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i23.4278 |
