| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Field of Vision |
| Article Title |
Molecular classifications of gastric cancers: Novel insights and possible future applications
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Silvio Ken Garattini, Debora Basile, Monica Cattaneo, Valentina Fanotto, Elena Ongaro, Marta Bonotto, Francesca V Negri, Rosa Berenato, Paola Ermacora, Giovanni Gerardo Cardellino, Mariella Giovannoni, Nicoletta Pella, Mario Scartozzi, Lorenzo Antonuzzo, Nicola Silvestris, Gianpiero Fasola and Giuseppe Aprile |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Giuseppe Aprile, MD, Department of Oncology, University and General Hospital, Via Pozzuolo 330, 33100 Udine, Italy. giuseppe.aprile@asuiud.sanita.fvg.it |
| Key Words |
Molecular biology; Immunotherapy; Gastric cancer; Classification; Targeted therapy |
| Core Tip |
TCGA individuates four molecular subtypes: Chromosomal instability, microsatellite instability, genomically stable and Epstein-Barr virus positive tumors. Asian Cancer Research Group classification partially overlaps with the previous one. Although not prospectively validated, these novel classifications suggest that different subtypes of gastric cancer might be treated with specific therapeutic strategies in the near future. |
| Publish Date |
2017-05-12 14:02 |
| Citation |
Garattini SK, Basile D, Cattaneo M, Fanotto V, Ongaro E, Bonotto M, Negri FV, Berenato R, Ermacora P, Cardellino GG, Giovannoni M, Pella N, Scartozzi M, Antonuzzo L, Silvestris N, Fasola G, Aprile G. Molecular classifications of gastric cancers: Novel insights and possible future applications. World J Gastrointest Oncol 2017; 9(5): 194-208 |
| URL |
http://www.wjgnet.com/1948-5204/full/v9/i5/194.htm |
| DOI |
http://dx.doi.org/10.4251/wjgo.v9.i5.194 |
