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Publication Name World Journal of Diabetes
Manuscript ID 2985
Country/Territory Egypt
Received
2013-03-30 18:40
Peer-Review Started
2013-03-31 20:50
To Make the First Decision
2013-05-02 10:33
Return for Revision
2013-05-03 14:26
Revised
2013-05-29 06:15
Second Decision
2013-07-11 08:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-07-11 13:12
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-07-31 15:30
Publish the Manuscript Online
2013-08-15 11:51
ISSN 1948-9358 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology and Metabolism
Manuscript Type Autobiography
Article Title Effect of treatment of overt hypothyroidism on insulin resistance
Manuscript Source Invited Manuscript
All Author List Aml Mohamed Nada
Funding Agency and Grant Number
Corresponding author Dr. Aml Mohamed Nada, MD, Lecturer, Department of Internal Medicine, Unit of Endocrinology, Diabetes and Metabolism, Faculty of Medicine, Mansoura University, El-Gomhoria Street, Mansoura 35516, Egypt. aml-nadanoha@yahoo.com
Keywords Hypothyroidism; Female; Thyroxine; Insulin resistance; Triglycerides; Cholesterol
Core Tip Thyroid dysfunction is the second most common endocrine disorder after diabetes mellitus. Both diseases are strong associated. Hypothyroidism is claimed to cause insulin resistance. Some available reports are in agreement and others are against this suggestion. In our study, we did not find a significant effect of hypothyroidism or thyroxine replacement on insulin resistance as calculated by insulin resistance was estimated using homeostasis model assessment. Thyroxine therapy leads to a significant reduction of total cholesterol but it does not change triglycerides. This may partially explain the association between hypothyroidism and dyslipidaemia as well as cardiovascular risk.
Publish Date 2013-08-15 11:51
Citation Nada AM, Effect of treatment of overt hypothyroidism on insulin resistance. World J Diabetes 2013; 4(4): 157-161
Url http://www.wjgnet.com/1948-9358/full/v4/i4/157.htm
DOI http://dx.doi.org/10.4239/wjd.v4.i4.157
Full Article (PDF) WJD-4-157.pdf
Manuscript File 2985-Review.docx
Answering Reviewers 2985-Answering reviewers.pdf
Copyright License Agreement 2985-Copyright assignment.pdf
Peer-review Report 2985-Peer review(s).pdf
Scientific Editor Work List 2985-Scientific editor work list.doc