Publication Name	World Journal of Diabetes
Manuscript ID	2985
Country	Egypt

Received	2013-03-30 18:40
Peer-Review Started	2013-03-31 20:50
To Make the First Decision	2013-05-02 10:33
Return for Revision	2013-05-03 14:26
Revised	2013-05-29 06:15
Second Decision	2013-07-11 08:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-07-11 13:12
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-31 15:30
Publish the Manuscript Online	2013-08-15 11:51

ISSN	1948-9358 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Autobiography
Article Title	Effect of treatment of overt hypothyroidism on insulin resistance
Manuscript Source	Invited Manuscript
All Author List	Aml Mohamed Nada
Funding Agency and Grant Number
Corresponding Author	Dr. Aml Mohamed Nada, MD, Lecturer, Department of Internal Medicine, Unit of Endocrinology, Diabetes and Metabolism, Faculty of Medicine, Mansoura University, El-Gomhoria Street, Mansoura 35516, Egypt. aml-nadanoha@yahoo.com
Key Words	Hypothyroidism; Female; Thyroxine; Insulin resistance; Triglycerides; Cholesterol
Core Tip	Thyroid dysfunction is the second most common endocrine disorder after diabetes mellitus. Both diseases are strong associated. Hypothyroidism is claimed to cause insulin resistance. Some available reports are in agreement and others are against this suggestion. In our study, we did not find a significant effect of hypothyroidism or thyroxine replacement on insulin resistance as calculated by insulin resistance was estimated using homeostasis model assessment. Thyroxine therapy leads to a significant reduction of total cholesterol but it does not change triglycerides. This may partially explain the association between hypothyroidism and dyslipidaemia as well as cardiovascular risk.
Publish Date	2013-08-15 11:51
Citation	Nada AM, Effect of treatment of overt hypothyroidism on insulin resistance. World J Diabetes 2013; 4(4): 157-161
URL	http://www.wjgnet.com/1948-9358/full/v4/i4/157.htm
DOI	http://dx.doi.org/10.4239/wjd.v4.i4.157

Full Article (PDF)	WJD-4-157.pdf
Manuscript File	2985-Review.docx
Answering Reviewers	2985-Answering reviewers.pdf
Copyright License Agreement	2985-Copyright assignment.pdf
Peer-review Report	2985-Peer review(s).pdf
Scientific Editor Work List	2985-Scientific editor work list.doc