Publication Name	World Journal of Gastroenterology
Manuscript ID	29868
Country	United States

Received	2016-08-30 08:59
Peer-Review Started	2016-09-01 18:34
To Make the First Decision	2016-09-20 08:33
Return for Revision	2016-09-22 19:49
Revised	2016-10-05 04:45
Second Decision	2016-11-07 13:13
Accepted by Journal Editor-in-Chief	2016-11-08 15:28
Accepted by Executive Editor-in-Chief	2016-11-13 15:24
Articles in Press	2016-11-13 15:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-29 11:05
Publish the Manuscript Online	2016-12-13 00:40

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Can probiotics benefit children with autism spectrum disorders?
Manuscript Source	Invited Manuscript
All Author List	Fernando Navarro, Yuying Liu and Jon Marc Rhoads
Funding Agency and Grant Number
Corresponding Author	Jon Marc Rhoads, MD, Professor of Pediatrics, Department of Pediatrics, the University of Texas Health Science Center at Houston McGovern Medical School, 6431 Fannin Street, MSB 3.137, Houston, TX 77030, United States. j.marc.rhoads@uth.tmc.edu
Key Words	Microbiome; Gastrointestinal; Inflammation; Functional bowel disease; Probiotics; Autism
Core Tip	Important new information has identified an abnormal intestinal microbial community in children with autism, an abnormality reported in many gastrointestinal (GI) conditions, including inflammatory bowel disease and irritable bowel syndrome (IBS). There is a complex interplay in these conditions between GI function (motility, secretion, permeability), the immune system, and the microbiota. Many parents of children with autism complain of GI symptoms, and they administer probiotics, a treatment which has been found to be safe and effective for adults with IBS. Future investigations are needed to determine if probiotic treatment would benefit the symptoms and behavior of these children.
Publish Date	2016-12-13 00:40
Citation	Navarro F, Liu Y, Rhoads JM. Can probiotics benefit children with autism spectrum disorders? World J Gastroenterol 2016; 22(46): 10093-10102
URL	http://www.wjgnet.com/1007-9327/full/v22/i46/10093.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i46.10093

Full Article (PDF)	WJG-22-10093.pdf
Full Article (Word)	WJG-22-10093.doc
Manuscript File	29868-Review.docx
Answering Reviewers	29868-Answering reviewers.pdf
Audio Core Tip	29868-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29868-Conflict-of-interest statement.pdf
Copyright License Agreement	29868-Copyright assignment.pdf
Peer-review Report	29868-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	29868-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	29868-Scientific misconduct check.pdf
Scientific Editor Work List	29868-Scientific editor work list.pdf