Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	29932
Country	Japan

Received	2016-08-31 10:57
Peer-Review Started	2016-09-02 10:12
To Make the First Decision	2016-10-20 08:48
Return for Revision	2016-10-31 09:20
Revised	2016-11-01 15:53
Second Decision	2016-12-12 08:37
Accepted by Journal Editor-in-Chief	2016-12-13 04:21
Accepted by Executive Editor-in-Chief	2016-12-19 11:04
Articles in Press	2016-12-19 11:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-01-12 17:33
Publish the Manuscript Online	2017-01-20 16:40

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Regenerative medicine using dental pulp stem cells for liver diseases
Manuscript Source	Invited Manuscript
All Author List	Shogo Ohkoshi, Hajime Hara, Haruka Hirono, Kazuhiko Watanabe and Katsuhiko Hasegawa
Funding Agency and Grant Number	Funding Agency Grant Number Japan Society for the Promotion of Science 25461012
Corresponding Author	Department of Internal Medicine, School of Life Dentistry at Niigata, Nippon Dental University, 1-8 Hamaura-Cho, Chuo-ku 951-8580, Niigata-city, Japan. okoshi@ngt.ndu.ac.jp
Key Words	Dental pulp; Mesenchymal stem cell; Regenerative medicine; Liver disease; Tooth bank
Core Tip	Dental pulp contains a mesenchymal stem cell population that has a similar gene expression pattern to that of the bone marrow and differentiates into cells of multi-cellular lineages. There have been several reports showing hepatic differentiation of this stem cell population in the presence of specific growth factors in serum-free culture medium. Their self-renewal and high proliferative capacities verify their stem-cell character and suggest that they are a promising cell source of regenerative medicine for refractory liver diseases. Currently, these cells are in the stage of animal studies to prove the efficacy and safety of dental pulp stem cell-based medicine for liver diseases.
Publish Date	2017-01-20 16:40
Citation	Ohkoshi S, Hara H, Hirono H, Watanabe K, Hasegawa K. Regenera­tive medicine using dental pulp stem cells for liver diseases. World J Gastrointest Pharmacol Ther 2017; 8(1): 1-6
URL	http://www.wjgnet.com/2150-5349/full/v8/i1/1.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v8.i1.1

Full Article (PDF)	WJGPT-8-1.pdf
Full Article (Word)	WJGPT-8-1.doc
Manuscript File	29932-Review.docx
Answering Reviewers	29932-Answering reviewers.pdf
Audio Core Tip	29932-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29932-Conflict-of-interest statement.pdf
Copyright License Agreement	29932-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	29932-Grant application form(s).pdf
Peer-review Report	29932-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	29932-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	29932-Scientific misconduct check.pdf
Scientific Editor Work List	29932-Scientific editor work list.pdf