Publication Name	World Journal of Transplantation
Manuscript ID	30125
Country	Italy

Received	2016-09-13 09:12
Peer-Review Started	2016-09-13 18:48
To Make the First Decision	2016-10-21 08:56
Return for Revision	2016-10-21 11:13
Revised	2016-10-26 22:06
Second Decision	2016-11-01 09:49
Accepted by Journal Editor-in-Chief	2016-11-01 23:43
Accepted by Executive Editor-in-Chief	2016-11-17 14:24
Articles in Press	2016-11-17 14:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-05 14:35
Publish the Manuscript Online	2016-12-14 14:32

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Transplantation
Manuscript Type	Review
Article Title	Complement related kidney diseases: Recurrence after transplantation
Manuscript Source	Invited Manuscript
All Author List	Maurizio Salvadori and Elisabetta Bertoni
Funding Agency and Grant Number
Corresponding Author	Maurizio Salvadori, MD, Department of Renal Transplantation, Careggi University Hospital, viale Pieraccini 18, 50139 Florence, Italy. maurizio.salvadori1@gmail.com
Key Words	Kidney disease recurrence; Complement dysregulation; Atypical hemolytic uremic syndrome; C3 glomerulopathies; Dense deposit disease; Plasma therapy; Eculizumab; C3 glomerulonephritis
Core Tip	Complement cascade is an important pathway of several kidney diseases. A distinction should be made between kidney diseases with complement overactivation and those with complement dysregulation. The latter are related to congenital or acquired abnormalities of complement factors. These diseases are linked to constitutional abnormalities of the patients, have high recurrence rate after renal transplantation and represent an important cause of graft loss. Diagnosis and treatment are not easy to be made. Just in the last decade a growing knowledge in the field of genetic and biology allowed the complement inhibitors to be the first class drug in the treatment.
Publish Date	2016-12-14 14:32
Citation	Salvadori M, Bertoni E. Complement related kidney diseases: Recurrence after transplantation. World J Transplant 2016; 6(4): 632-645
URL	http://www.wjgnet.com/2220-3230/full/v6/i4/632.htm
DOI	http://dx.doi.org/10.5500/wjt.v6.i4.632

Full Article (PDF)	WJT-6-632.pdf
Full Article (Word)	WJT-6-632.doc
Manuscript File	30125-Review.docx
Answering Reviewers	30125-Answering reviewers.pdf
Audio Core Tip	30125-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	30125-Conflict-of-interest statement.pdf
Copyright License Agreement	30125-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	30125-Language certificate.pdf
Peer-review Report	30125-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	30125-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	30125-Scientific misconduct check.pdf
Scientific Editor Work List	30125-Scientific editor work list.pdf