Publication Name	World Journal of Experimental Medicine
Manuscript ID	30140
Country	Brazil

Received	2016-09-14 09:15
Peer-Review Started	2016-09-14 18:23
To Make the First Decision	2016-10-21 08:56
Return for Revision	2016-10-21 11:57
Revised	2016-11-01 08:23
Second Decision	2016-11-17 16:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-11-29 09:02
Articles in Press	2016-11-29 09:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-02-09 15:06
Publish the Manuscript Online	2017-02-17 10:11

ISSN	2220-315x (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Allergy
Manuscript Type	Review
Article Title	Odd couple: The unexpected partnership of glucocorticoid hormones and cysteinyl-leukotrienes in the extrinsic regulation of murine bone-marrow eosinopoiesis
Manuscript Source	Invited Manuscript
All Author List	Pedro Xavier-Elsas, Daniela Masid-de-Brito, Bruno Marques Vieira and Maria Ignez C Gaspar-Elsas
Funding Agency and Grant Number
Corresponding Author	Pedro Xavier-Elsas, MD, PhD, Associate Professor, Department Immunology, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Bloco I, Room I-2-066, Rio de Janeiro 21941-590, Brazil. pxelsas@micro.ufrj.br
Key Words	Bone marrow; Leukotriene; Eosinophil; Stress; Glucocorticoid
Core Tip	The bone-marrow is exquisitely sensitive to regulation by systemic events, which selectively increase production of different blood cell types to meet transient increases in demand following injury. An association between stress and allergy has long been known, but its mechanisms remain incompletely understood. The exploration of underlying mechanisms in a variety of murine models yielded evidence of separate but inter?related roles for adrenal glucocorticoid hormones and cysteinyl-leukotrienes in coupling systemic events to bone-marrow responses in vivo. We here discuss how these unlikely partners work together to promote eosinophilia but through subtle mechanisms also limit its magnitude.
Publish Date	2017-02-17 10:11
Citation	Xavier-Elsas P, Masid-de-Brito D, Vieira BM, Gaspar-Elsas MIC. Odd couple: The unexpected partnership of glucocorticoid hormones and cysteinyl-leukotrienes in the extrinsic regulation of murine bone-marrow eosinopoiesis. World J Exp Med 2017; 7(1): 11-24
URL	http://www.wjgnet.com/2220-315X/full/v7/i1/11.htm
DOI	http://dx.doi.org/10.5493/wjem.v7.i1.11

Full Article (PDF)	WJEM-7-11.pdf
Full Article (Word)	WJEM-7-11.doc
Manuscript File	30140-Review.docx
Answering Reviewers	30140-Answering reviewers.pdf
Audio Core Tip	30140-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	30140-Conflict-of-interest statement.pdf
Copyright License Agreement	30140-Copyright assignment.pdf
Peer-review Report	30140-Peer-review(s).pdf
Scientific Misconduct Check	30140-Scientific misconduct check.pdf
Scientific Editor Work List	30140-Scientific editor work list.pdf