Publication Name	World Journal of Orthopedics
Manuscript ID	30182
Country	Indonesia

Received	2016-09-17 19:11
Peer-Review Started	2016-09-19 10:20
To Make the First Decision	2016-10-21 09:00
Return for Revision	2016-10-21 13:48
Revised	2016-11-18 00:56
Second Decision	2016-11-29 09:57
Accepted by Journal Editor-in-Chief	2016-12-02 01:33
Accepted by Executive Editor-in-Chief	2016-12-09 17:43
Articles in Press	2016-12-09 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-02-09 15:07
Publish the Manuscript Online	2017-02-15 08:52

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Orthopedics
Manuscript Type	Case Control Study
Article Title	Interleukin-6 and ratio of plasma interleukin-6/interleukin-10 as risk factors of symptomatic lumbar osteoarthritis
Manuscript Source	Unsolicited Manuscript
All Author List	I Ketut Suyasa, I Ketut Siki Kawiyana, I Made Bakta and I Gde Raka Widiana
Funding Agency and Grant Number
Corresponding Author	Dr. I Ketut Suyasa, SpB, SpOT(K) Spine, Department of Orthopaedic and Traumatology, Faculty of Medicine, Udayana University Sanglah General Hospital, Denpasar, Bali 80113, Indonesia. iksysa@gmail.com
Key Words	Symptomatic lumbar osteoarthritis; Ratio of interleukin-6/interleukin-10; Interleukin-6; Interleukin-10; Cartilage oligomeric matrix protein
Core Tip	High levels of cartilage oligomeric matrix protein in estrogen deficiency postmenopausal women were not at risk for symptomatic lumbar osteoarthritis (OA). Estrogen-deficient postmenopausal women with the high levels of interleukin (IL)-6 had higher risk for symptomatic lumbar OA from the low level of IL-6. At lower levels of IL-10, there was no risk for symptomatic lumbar OA than with the higher levels of IL-10. High ratio of IL-6/IL-10 levels in estrogen deficiency postmenopausal women produced higher risk for symptomatic lumbar OA.
Publish Date	2017-02-15 08:52
Citation	Suyasa IK, Kawiyana IKS, Bakta IM, Widiana IGR. Interleukin-6 and ratio of plasma interleukin-6/interleukin-10 as risk factors of symptomatic lumbar osteoarthritis. World J Orthop 2017; 8(2): 149-155
URL	http://www.wjgnet.com/2218-5836/full/v8/i2/149.htm
DOI	http://dx.doi.org/10.5312/wjo.v8.i2.149

Full Article (PDF)	WJO-8-149.pdf
Full Article (Word)	WJO-8-149.doc
Manuscript File	30182-Review.doc
Answering Reviewers	30182-Answering reviewers.pdf
Audio Core Tip	30182-Audio core tip.mp3
Biostatistics Review Certificate	30182-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	30182-Conflict-of-interest statement.pdf
Copyright License Agreement	30182-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	30182-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	30182-Language certificate.pdf
Peer-review Report	30182-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	30182-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	30182-Scientific misconduct check.pdf
Scientific Editor Work List	30182-Scientific editor work list.pdf