Publication Name	World Journal of Cardiology
Manuscript ID	30206
Country	United Kingdom

Received	2016-09-20 11:27
Peer-Review Started	2016-09-23 09:57
To Make the First Decision	2016-11-11 09:07
Return for Revision	2016-11-21 17:11
Revised	2016-11-25 14:56
Second Decision	2017-03-13 10:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-03-22 16:21
Articles in Press	2017-03-22 16:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-17 10:59
Publish the Manuscript Online	2017-05-20 11:08

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Empirical anticoagulation for patients in sinus rhythm at high risk of ischaemic stroke: A review of current literature
Manuscript Source	Invited Manuscript
All Author List	Irma Battipaglia, James O’Neill, Andrew J Hogarth and Muzahir H Tayebjee
Funding Agency and Grant Number
Corresponding Author	Dr. Muzahir H Tayebjee, MB ChB (Hons), MRCP, MD, Department of Cardiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, United Kingdom. mhtayebjee@hotmail.com
Key Words	Anticoagulation; Ischaemic stroke; Atrial fibrillation; CHA2DS2VASc; CHADS-2; Heart failure; Coronary artery disease; Peripheral arterial disease
Core Tip	This is a contemporary review exploring issues related to the risk of stroke and use of anticoagulation in patients who are in sinus rhythm (SR). It examines the prediction of stroke in patients without known atrial fibrillation (AF), the identification of AF in patients following stroke and the use of anticoagulation in post-stroke patients seemingly in SR or those at high-risk of stroke. The main findings are: (1) prolonged cardiac monitoring increases the rate of AF diagnosis but is not cost-effective; (2) current risk stratification schemes such as CHA2DS2VASc can identify those in sinus rhythm who are at risk of stroke; and (3) further research is required to determine whether individuals at high-risk of stroke would benefit from anticoagulation.
Publish Date	2017-05-20 11:08
Citation	Battipaglia I, O’Neill J, Hogarth AJ, Tayebjee MH. Empirical anticoagulation for patients in sinus rhythm at high risk of ischaemic stroke: A review of current literature. World J Cardiol 2017; 9(5): 422-428
URL	http://www.wjgnet.com/1949-8462/full/v9/i5/422.htm
DOI	http://dx.doi.org/10.4330/wjc.v9.i5.422

Full Article (PDF)	WJC-9-422.pdf
Full Article (Word)	WJC-9-422.doc
Manuscript File	30206-Review.docx
Answering Reviewers	30206-Answering reviewers.pdf
Audio Core Tip	30206-Audio core tip.wav
Conflict-of-Interest Disclosure Form	30206-Conflict-of-interest statement.pdf
Copyright License Agreement	30206-Copyright assignment.pdf
Peer-review Report	30206-Peer-review(s).pdf
Scientific Misconduct Check	30206-Scientific misconduct check.pdf
Scientific Editor Work List	30206-Scientific editor work list.pdf