Publication Name	World Journal of Gastroenterology
Manuscript ID	30220
Country	United States

Received	2016-09-20 09:13
Peer-Review Started	2016-09-20 21:04
To Make the First Decision	2016-10-10 13:26
Return for Revision	2016-10-13 17:30
Revised	2016-11-23 04:24
Second Decision	2016-12-16 17:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-12-21 16:11
Articles in Press	2016-12-21 16:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-01-09 19:35
Publish the Manuscript Online	2017-01-22 11:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Is endoscopic ultrasound examination necessary in the management of esophageal cancer?
Manuscript Source	Invited Manuscript
All Author List	Tomas DaVee, Jaffer A Ajani and Jeffrey H Lee
Funding Agency and Grant Number
Corresponding Author	Jeffrey H Lee, MD, MPH, FASGE, FACG, AGAF, Department of Gastroenterology, Hepatology and Nutrition, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit Number 1466, Houston, TX 77030, United States. jefflee@mdanderson.org
Key Words	Esophageal squamous cell carcinoma; Endosonography; Echoendoscope; Esophagus cancer; Esophageal adenocarcinoma
Core Tip	Endoscopic ultrasound (EUS) is not necessary or adds little in management of many cases, such as, in patients with distant metastases or following pre-operative (neoadjuvant) chemoradiotherapy. EUS is the most sensitive test to exclude local tumor invasion and regional nodal disease that would make endoscopic resection (ER) unsafe or unnecessary. Thus, for early esophageal cancer staging, EUS followed by ER and histopathologic analysis, remains the standard-of-care. For a minority of locally advanced cancers, EUS-fine-needle aspiration can define the radiotherapy field by providing tissue samples of suspicious lymph nodes that are remote from the primary tumor.
Publish Date	2017-01-22 11:39
Citation	DaVee T, Ajani JA, Lee JH. Is endoscopic ultrasound examination necessary in the management of esophageal cancer? World J Gastroenterol 2017; 23(5): 751-762
URL	http://www.wjgnet.com/1007-9327/full/v23/i5/751.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i5.751

Full Article (PDF)	WJG-23-751.pdf
Full Article (Word)	WJG-23-751.doc
Manuscript File	30220-Review.docx
Answering Reviewers	30220-Answering reviewers.pdf
Audio Core Tip	30220-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	30220-Conflict-of-interest statement.pdf
Copyright License Agreement	30220-Copyright assignment.pdf
Supplementary Material	Supplementary_Material_20160920073037.docx
Peer-review Report	30220-Peer-review(s).pdf
Scientific Misconduct Check	30220-Scientific misconduct check.pdf
Scientific Editor Work List	30220-Scientific editor work list.pdf