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Articles Published Processes
4/7/2017 8:24:11 AM | Browse: 1071 | Download: 1498
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Received |
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2016-09-21 09:01 |
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Peer-Review Started |
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2016-09-23 10:36 |
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To Make the First Decision |
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2016-10-20 08:45 |
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Return for Revision |
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2016-11-02 15:41 |
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Revised |
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2016-11-21 08:01 |
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Second Decision |
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2017-01-04 16:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-01-14 14:38 |
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Articles in Press |
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2017-01-14 14:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-03-30 14:42 |
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Publish the Manuscript Online |
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2017-04-07 08:24 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Watch and wait policy in advanced neuroendocrine tumors: What does it mean?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nicola Fazio |
| Funding Agency and Grant Number |
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| Corresponding Author |
Nicola Fazio, MD, PhD, Unit of gastrointestinal medical oncology and neuroendocrine tumors, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy. nicola.fazio@ieo.it |
| Key Words |
Observation; Wait and see; Watch and wait; Surveillance; Neuroendocrine tumors |
| Core Tip |
Watch and wait (W and W) is a term coined to indicate observation without therapy assessing the evolution of the tumor. Given that neuroendocrine tumors sometimes are radiologically stable over months since they tend to grow slowly observation has been reported as an option to be considered in several guidelines and recommendations. However it has neither validated nor specifically investigated so far. Therefore its application in clinical practice is arbitrary and it differs in terms of tumor status assessment, type and timing of imaging or other exams utilized. While undertaking W and W to delay the first-line therapy by some weeks may be justified in good performance asymptomatic patients with low-grade neuroendocrine neoplasms (NENs) in order to usefully characterize the disease and patient and thereby choose the best therapy and therapeutic strategy, it seems to be far more difficult to justify W and W with the intent of avoiding an anti-tumor treatment. It should be considered that not only do NENs tend to grow even when they have very favorable biological characteristics but also that the alternative to W and W is most commonly a low toxic and effective treatment with somatostatin analogs. |
| Publish Date |
2017-04-07 08:24 |
| Citation |
Fazio N. Watch and wait policy in advanced neuroendocrine tumors: What does it mean? World J Clin Oncol 2017; 8(2): 96-99 |
| URL |
http://www.wjgnet.com/2218-4333/full/v8/i2/96.htm |
| DOI |
http://dx.doi.org/10.5306/wjco.v8.i2.96 |
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