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Articles Published Processes
3/6/2017 1:27:00 PM | Browse: 873 | Download: 1489
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Received |
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2016-09-22 10:14 |
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Peer-Review Started |
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2016-09-22 17:46 |
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To Make the First Decision |
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2016-12-19 11:29 |
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Return for Revision |
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2016-12-19 15:29 |
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Revised |
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2016-12-27 12:51 |
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Second Decision |
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2017-01-16 13:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-01-17 16:54 |
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Articles in Press |
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2017-01-17 16:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-02-06 19:56 |
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Typeset the Manuscript |
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2017-02-23 17:43 |
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Publish the Manuscript Online |
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2017-03-06 13:24 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Case Control Study |
| Article Title |
Association between TLR7 copy number variations and hepatitis B virus infection outcome in Chinese
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fang Li, Xu Li, Gui-Zhou Zou, Yu-Feng Gao and Jun Ye |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81273142 |
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| Corresponding Author |
Xu Li, Professor, Department of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei 230022, Anhui Province, China. aaylixu@qq.com |
| Key Words |
Toll-like receptor 7; Hepatitis B virus; Copy number variations; Gene susceptibility |
| Core Tip |
Differences in patient genetic backgrounds may influence the quality of the immune response and may result in different hepatitis B virus (HBV) infection outcomes. Toll-like receptor 7 (TLR7) is involved in the sensing of viruses and priming of the subsequent immune response. We investigated the association between copy number at the TLR7 locus and genetic susceptibility to chronic HBV infection. Comparison of individuals with chronic and acute HBV revealed that low TLR7 copy number was associated with chronic but not acute HBV in both males and females, though it was not associated with subsequent disease progression. |
| Publish Date |
2017-03-06 13:24 |
| Citation |
Li F, Li X, Zou GZ, Gao YF, Ye J. Association between TLR7 copy number variations and hepatitis B virus infection outcome in Chinese. World J Gastroenterol 2017; 23(9): 1602-1607 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i9/1602.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i9.1602 |
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