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3/6/2017 1:27:00 PM | Browse: 787 | Download: 1162
Publication Name World Journal of Gastroenterology
Manuscript ID 30246
Country/Territory China
Received
2016-09-22 10:14
Peer-Review Started
2016-09-22 17:46
To Make the First Decision
2016-12-19 11:29
Return for Revision
2016-12-19 15:29
Revised
2016-12-27 12:51
Second Decision
2017-01-16 13:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-01-17 16:54
Articles in Press
2017-01-17 16:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-02-06 19:56
Typeset the Manuscript
2017-02-23 17:43
Publish the Manuscript Online
2017-03-06 13:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Case Control Study
Article Title Association between TLR7 copy number variations and hepatitis B virus infection outcome in Chinese
Manuscript Source Unsolicited Manuscript
All Author List Fang Li, Xu Li, Gui-Zhou Zou, Yu-Feng Gao and Jun Ye
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81273142
Corresponding Author Xu Li, Professor, Department of Infectious Disease, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei 230022, Anhui Province, China. aaylixu@qq.com
Key Words Toll-like receptor 7; Hepatitis B virus; Copy number variations; Gene susceptibility
Core Tip Differences in patient genetic backgrounds may influence the quality of the immune response and may result in different hepatitis B virus (HBV) infection outcomes. Toll-like receptor 7 (TLR7) is involved in the sensing of viruses and priming of the subsequent immune response. We investigated the association between copy number at the TLR7 locus and genetic susceptibility to chronic HBV infection. Comparison of individuals with chronic and acute HBV revealed that low TLR7 copy number was associated with chronic but not acute HBV in both males and females, though it was not associated with subsequent disease progression.
Publish Date 2017-03-06 13:24
Citation Li F, Li X, Zou GZ, Gao YF, Ye J. Association between TLR7 copy number variations and hepatitis B virus infection outcome in Chinese. World J Gastroenterol 2017; 23(9): 1602-1607
URL http://www.wjgnet.com/1007-9327/full/v23/i9/1602.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i9.1602
Full Article (PDF) WJG-23-1602.pdf
Full Article (Word) WJG-23-1602.doc
Manuscript File 30246-Review.doc
Answering Reviewers 30246-Answering reviewers.pdf
Audio Core Tip 30246-Audio core tip.wma
Biostatistics Review Certificate 30246-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 30246-Conflict-of-interest statement.pdf
Copyright License Agreement 30246-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) Grant_Application_Form_20160921212952.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160921213122.doc
Institutional Review Board Approval Form or Document 30246-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 30246-Language certificate.pdf
Peer-review Report 30246-Peer-review(s).pdf
Scientific Misconduct Check 30246-Scientific misconduct check.pdf
Scientific Editor Work List 30246-Scientific editor work list.pdf