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Articles Published Processes
1/14/2017 10:42:00 AM | Browse: 977 | Download: 1975
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Received |
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2016-09-23 14:04 |
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Peer-Review Started |
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2016-09-23 21:03 |
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To Make the First Decision |
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2016-11-09 08:16 |
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Return for Revision |
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2016-11-11 16:32 |
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Revised |
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2016-11-25 03:20 |
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Second Decision |
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2016-12-16 17:22 |
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Accepted by Journal Editor-in-Chief |
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2016-12-16 17:30 |
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Accepted by Executive Editor-in-Chief |
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2016-12-21 16:12 |
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Articles in Press |
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2016-12-21 16:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-12-28 20:31 |
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Publish the Manuscript Online |
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2017-01-14 10:27 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
α2-Heremans-schmid glycoprotein (fetuin A) downregulation and its utility in inflammatory bowel disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Anastassios C Manolakis, Gregory Christodoulidis, Andreas N Kapsoritakis, Panagiotis Georgoulias, Elisavet K Tiaka, Kostas Oikonomou, Varvara J Valotassiou and Spyros P Potamianos |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Hellenic Society of Gastroenterology |
5496 |
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| Corresponding Author |
Gregory Christodoulidis, MD, PhD, Department of Surgery, University of Thessaly, School of Medicine, Filellinon, 41110 Mezourlo, Larissa, Greece. gregsurg@yahoo.gr |
| Key Words |
Inflammatory bowel disease; Irritable bowel syndrome; Fetuin A |
| Core Tip |
α2-Heremans-Schmid Glycoprotein (AHSG/fetuin A) a multi-task negative acute-phase protein is downregulated in patients with inflammatory bowel disease (IBD). Based on this significant decrease a discrimination between IBD patients with either Crohn's disease or ulcerative colitis and those with irritable bowel syndrome or healthy controls can be made. A more robust AHSG decrease correlates well with and predicts complicated disease behavior, need for biological therapy and surgery, within three years from diagnosis. These associations are supported by additional links between AHSG and acute-phase markers i.e., C-reactive protein or serological markers linked to IBD course i.e., anti-glycan antibodies. |
| Publish Date |
2017-01-14 10:27 |
| Citation |
Manolakis AC, Christodoulidis G, Kapsoritakis AN, Georgoulias P, Tiaka EK, Oikonomou K, Valotassiou VJ, Potamianos SP. α2-Heremans-schmid glycoprotein (fetuin A) downregulation and its utility in inflammatory bowel disease. World J Gastroenterol 2017; 23(3): 437-446 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i3/437.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i3.437 |
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