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Articles Published Processes
2/26/2017 6:20:00 PM | Browse: 963 | Download: 1458
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Received |
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2016-10-07 16:36 |
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Peer-Review Started |
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2016-10-08 18:40 |
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To Make the First Decision |
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2016-12-19 11:29 |
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Return for Revision |
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2016-12-20 10:42 |
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Revised |
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2017-01-13 09:58 |
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Second Decision |
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2017-01-16 13:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-01-17 16:57 |
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Articles in Press |
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2017-01-17 16:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-02-04 11:51 |
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Typeset the Manuscript |
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2017-02-16 20:04 |
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Publish the Manuscript Online |
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2017-02-26 18:20 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Different phenotypes of monocytes in patients with new-onset mild acute pancreatitis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Man-Li Zhang, Yan-Fang Jiang, Xin-Rui Wang, Li-Li Ding, Hong-Juan Wang, Qing-Qing Meng and Pu-Jun Gao |
| Funding Agency and Grant Number |
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| Corresponding Author |
Pu-Jun Gao, MD, PhD, Department of Hepatology, The First Hospital of Jilin University, 71 Xinmin Street, Changchun 130021, Jilin Province, China. pujun-gao@163.com |
| Key Words |
Mild acute pancreatitis; Monocyte; Cytokine; Acute physiology and chronic health evaluation II score; C-reactive protein |
| Core Tip |
This is the first study on the numbers of different phenotypes of peripheral blood monocytes in patients with new-onset mild acute pancreatitis (MAP). Increased numbers of CD14+CD163- and CD14+CD163-MAC387+ M1 monocytes were positively correlated with the levels of plasma C-reactive protein (CRP), which suggest that pro-inflammatory monocytes may participate in the pathogenesis of MAP. The increased numbers of CD14+CD163+CD115+ M2 monocytes were positively correlated with the plasma CRP levels and the acute physiology and chronic health evaluation II scores, suggesting that the numbers of CD14+CD163+CD115+ monocytes may be a valuable biomarker for evaluating the severity of MAP. Our findings may provide new insights into the pathogenic process and immunoregulation of MAP. |
| Publish Date |
2017-02-26 18:20 |
| Citation |
Zhang ML, Jiang YF, Wang XR, Ding LL, Wang HJ, Meng QQ, Gao PJ. Different phenotypes of monocytes in patients with new-onset mild acute pancreatitis. World J Gastroenterol 2017; 23(8): 1477-1488 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i8/1477.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i8.1477 |
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