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2/26/2017 6:20:00 PM | Browse: 1051 | Download: 1705
Publication Name World Journal of Gastroenterology
Manuscript ID 30515
Country China
Received
2016-10-07 15:37
Peer-Review Started
2016-10-07 16:38
To Make the First Decision
2016-10-20 12:59
Return for Revision
2016-10-27 08:58
Revised
2016-11-06 14:17
Second Decision
2016-11-22 20:02
Accepted by Journal Editor-in-Chief
2016-11-23 20:40
Accepted by Company Editor-in-Chief
2017-01-11 11:40
Articles in Press
2017-01-11 11:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-01-25 10:27
Typeset the Manuscript
2017-02-13 16:01
Publish the Manuscript Online
2017-02-26 18:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Integrative & Complementary Medicine
Manuscript Type Basic Study
Article Title Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis
Manuscript Source Unsolicited Manuscript
All Author List Yu-Mei Zhang, Hong-Yu Ren, Xian-Lin Zhao, Juan Li, Jun-Yi Li, Fu-Sheng Wu, Hang Su and Wen-Fu Tang
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China 81374042
the National Natural Science Foundation of China 81370091
the National Natural Science Foundation of China 81573857
Corresponding Author Dr. Wen-Fu Tang, Professor, Sichuan Provincial Pancreatitis Center, Department of Integrative Medicine, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, Sichuan Province, China. hxtangwenfu@126.com
Key Words Pharmacokinetics; Pharmacodynamics; Da-Cheng-Qi decoction; Acute pancreatitis; Acute liver injury
Core Tip Our study group had raised the herbal recipe tissue pharmacology hypothesis, which assumed that the effect of herb formula is related to its target tissue distributions or concentrations of the effective components in target tissues. This study was to investigate the mechanism by which Da-Cheng-Qi decoction (DCQD) ameliorates acute liver injury complicated with severe acute pancreatitis in rats by detecting the tissue distributions of the components from DCQD in the liver and the inflammatory mediators as well as the pathological scores.
Publish Date 2017-02-26 18:20
Citation Zhang YM, Ren HY, Zhao XL, Li J, Li JY, Wu FS, Su H, Tang WF. Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis. World J Gastroenterol 2017; 23(8): 1367-1374
URL http://www.wjgnet.com/1007-9327/full/v23/i8/1367.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i8.1367
Full Article (PDF) WJG-23-1367.pdf
Full Article (Word) WJG-23-1367.doc
Manuscript File 30515-Review.doc
Answering Reviewers 30515-Answering reviewers.pdf
Audio Core Tip 30515-Audio core tip.mp3
Biostatistics Review Certificate 30515-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 30515-Conflict-of-interest statement.pdf
Copyright License Agreement 30515-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 30515-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 30515-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 30515-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 30515-Language certificate.pdf
Supplementary Material Supplementary_Material_20161005220437.pdf
Peer-review Report 30515-Peer-reivew(s).pdf
Journal Editor-in-Chief Review Report 30515-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 30515-Scientific misconduct check.pdf
Scientific Editor Work List 30515-Scientific editor work list.pdf