Publication Name	World Journal of Gastroenterology
Manuscript ID	30625
Country	China

Received	2016-10-11 09:40
Peer-Review Started	2016-10-12 10:40
To Make the First Decision	2016-12-02 08:19
Return for Revision	2016-12-12 16:31
Revised	2017-01-09 19:16
Second Decision	2017-02-06 14:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-02-08 09:53
Articles in Press	2017-02-08 09:54
Publication Fee Transferred
Edit the Manuscript by Language Editor	2017-03-14 15:52
Typeset the Manuscript	2017-03-22 20:45
Publish the Manuscript Online	2017-04-06 18:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Basic Study
Article Title	MicroRNA-145 exerts tumor-suppressive and chemo-resistance lowering effects by targeting CD44 in gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Jian-Feng Zeng, Xiao-Qiu Ma, Lin-Pei Wang and Wei Wang
Funding Agency and Grant Number	Funding Agency Grant Number Quanzhou excellent personnel training 10A16 Natural Science Foundation of Fujian Province JA08084 Fujian Medical University 092D014
Corresponding Author	Dr. Wei Wang, Department of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Zhongshanbei Road 34, Quanzhou 362000, Fujian Province, China. wanglinpei@126.com
Key Words	miR-145; CD44; Gastric cancer stem cells; Chemo-resistance
Core Tip	The levels of CD44 and miR-145 are related strongly to stemness properties in gastric cancer. The aim of this investigation was to determine the underlying molecular mechanism involved in this relationship. The findings demonstrated that miR-145 regulates CD44 expression by directly targeting its 3’-untranslated region, which might play a critical role in the regulation of tumor growth and chemo-resistance in gastric cancer.
Publish Date	2017-04-06 18:30
Citation	Zeng JF, Ma XQ, Wang LP, Wang W. MicroRNA-145 exerts tumor-suppressive and chemo-resistance lowering effects by targeting CD44 in gastric cancer. World J Gastroenterol 2017; 23(13): 2337-2345
URL	http://www.wjgnet.com/1007-9327/full/v23/i13/2337.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i13.2337

Full Article (PDF)	WJG-23-2337.pdf
Full Article (Word)	WJG-23-2337.doc
Manuscript File	30625-Review.docx
Answering Reviewers	30625-Answering reviewer.pdf
Audio Core Tip	30625-Audio core tip.MP3
Biostatistics Review Certificate	30625-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	30625-Conflict-of-interest statment.pdf
Copyright License Agreement	30625-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	30625-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	30625-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	30625-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	30625-Language certificate.pdf
Peer-review Report	30625-Peer-review(s).pdf
Scientific Misconduct Check	30625-Scientific misconduct check.pdf
Scientific Editor Work List	30625-Scientific editor work list.pdf